Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells (Q39930114)

15 September 2017

Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells (English)

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15 September 2017

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S H Lee

1

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15 September 2017

J Kim

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2

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15 September 2017

W-H Kim

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3

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15 September 2017

Y M Lee

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4

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15 September 2017

language of work or name

English

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publication date

13 October 2008

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15 September 2017

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15 September 2017

28

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15 September 2017

184-194

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15 September 2017

2

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https://scigraph.springernature.com/pub.10.1038/onc.2008.377

15 September 2017

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Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

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Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

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Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines.

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Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells

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Role of RUNX family members in transcriptional repression and gene silencing

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Helicobacter pylori in gastric cancer established by CagA immunoblot as a marker of past infection.

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Regulation of E-cadherin expression by VHL and hypoxia-inducible factor.

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Histone modifying and chromatin remodelling enzymes in cancer and dysplastic syndromes

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Hypoxia--a key regulatory factor in tumour growth

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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Contribution of reactivated RUNX3 to inhibition of gastric cancer cell growth following suberoylanilide hydroxamic acid (vorinostat) treatment

31 March 2020

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RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.

31 March 2020

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Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13.

31 March 2020

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Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation

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NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells

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Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

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The epigenomics of cancer

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

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Causal relationship between the loss of RUNX3 expression and gastric cancer

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Transcriptional silencing of the RUNX3 gene by CpG hypermethylation is associated with lung cancer.

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Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci

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Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells

31 March 2020

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Decreased Expression of the DNA Mismatch Repair Gene Mlh1 under Hypoxic Stress in Mammalian Cells

31 March 2020

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31 March 2020

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

31 March 2020

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

31 March 2020

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Rb targets histone H3 methylation and HP1 to promoters

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

31 March 2020

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DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

31 March 2020

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

31 March 2020

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Angiogenesis in ischemic and neoplastic disorders

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Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kappaB and histone deacetylase 1 in ventricular myocytes

31 March 2020

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5-Aza-2'-deoxycytidine induces histone hyperacetylation of mouse centromeric heterochromatin by a mechanism independent of DNA demethylation

31 March 2020

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Synthesis of signals for de novo DNA methylation in Neurospora crassa

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.377

Helicobacter pylori infection and the development of gastric cancer

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.377

31 March 2020

Focus on gastric cancer.

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https://api.crossref.org/works/10.1038%2FONC.2008.377

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.377

Loss of RUNX3 expression significantly affects the clinical outcome of gastric cancer patients and its restoration causes drastic suppression of tumor growth and metastasis

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2008.377

DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe.

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2008.377

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15 September 2017

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