Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells (Q39934133)

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scientific article published on 30 September 2008

Language	Label	Description	Also known as
English	Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells	scientific article published on 30 September 2008

Statements

scholarly article

1 reference

Europe PubMed Central

15 September 2017

Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells (English)

1 reference

Europe PubMed Central

15 September 2017

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

author name string

Pinella Buongiorno

1

1 reference

Europe PubMed Central

15 September 2017

Vaijayanti V Pethe

2

1 reference

Europe PubMed Central

15 September 2017

George S Charames

3

1 reference

Europe PubMed Central

15 September 2017

Susmita Esufali

4

1 reference

Europe PubMed Central

15 September 2017

Bharati Bapat

5

1 reference

Europe PubMed Central

15 September 2017

publication date

30 September 2008

1 reference

Europe PubMed Central

15 September 2017

Molecular Cancer

1 reference

Europe PubMed Central

15 September 2017

7

1 reference

Europe PubMed Central

15 September 2017

73

1 reference

Europe PubMed Central

15 September 2017

https://scigraph.springernature.com/pub.10.1186/1476-4598-7-73

0 references

Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

CK2 controls the recruitment of Wnt regulators to target genes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase

1 reference

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22 September 2017

Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system

1 reference

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22 September 2017

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

1 reference

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22 September 2017

Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine

1 reference

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22 September 2017

Rho GTPase expression in tumourigenesis: evidence for a significant link

1 reference

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22 September 2017

Nuclear localization and chromatin targets of p21-activated kinase 1

1 reference

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22 September 2017

Tiam1 gene expression and its significance in colorectal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation

1 reference

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22 September 2017

Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Wnt/beta-catenin and estrogen signaling converge in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Pak-1 expression increases with progression of colorectal carcinomas to metastasis

1 reference

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22 September 2017

The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences

1 reference

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22 September 2017

Mutated APC and Asef are involved in the migration of colorectal tumour cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Opposite regulation of myc and p21waf1 transcription by STAT3 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Vav1 is a component of transcriptionally active complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

A new nuclear component of the Wnt signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Rho family proteins: coordinating cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

All Tcf HMG box transcription factors interact with Groucho-related co-repressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Asef, a link between the tumor suppressor APC and G-protein signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

XCtBP is a XTcf-3 co-repressor with roles throughout Xenopus development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Identification of c-MYC as a target of the APC pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

1 reference

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22 September 2017

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

22 September 2017

Functional characterization of multiple transactivating elements in beta-catenin, some of which interact with the TATA-binding protein in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

25 September 2017

Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

15 June 2018

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

20 August 2018

Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

20 August 2018

Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

20 August 2018

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1 reference

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20 August 2018

Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

20 August 2018

Rho GTPases are over-expressed in human tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

20 August 2018

Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2565678

20 August 2018

Molecular detection of circulating cancer cells in the peripheral blood of patients with colorectal cancer by using membrane array with a multiple mRNA marker panel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826597

12 December 2020

based on heuristic

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CBP/p300 Integrates Raf/Rac-Signaling Pathways in the Transcriptional Induction of NF-ATc during T Cell Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18826597

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-7-73

1 reference

Europe PubMed Central

15 September 2017

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1476-4598-7-73

1 reference

Europe PubMed Central

15 September 2017

1 reference

Europe PubMed Central

15 September 2017

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