Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders? (Q39952627)

15 September 2017

Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders? (English)

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15 September 2017

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M Hallschmid

1

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PubMed ID

19705099

15 September 2017

B Schultes

series ordinal

2

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15 September 2017

25 August 2009

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15 September 2017

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15 September 2017

52

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15 September 2017

11

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15 September 2017

2264-2269

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https://scigraph.springernature.com/pub.10.1007/s00125-009-1501-x

15 September 2017

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cites work

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype.

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Crossref

https://api.crossref.org/works/10.1007%2FS00125-009-1501-X

Intranasal insulin attenuates the hypothalamic-pituitary-adrenal axis response to psychosocial stress

21 January 2018

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12 December 2020

Attenuation of insulin-evoked responses in brain networks controlling appetite and reward in insulin resistance: the cerebral basis for impaired control of food intake in metabolic syndrome?

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12 December 2020

The cerebrocortical response to hyperinsulinemia is reduced in overweight humans: a magnetoencephalographic study

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12 December 2020

An obesity-associated FTO gene variant and increased energy intake in children

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12 December 2020

Insulin receptors are widely distributed in the central nervous system of the rat

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12 December 2020

Cerebrocortical beta activity in overweight humans responds to insulin detemir

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12 December 2020

Intranasal insulin improves memory in humans

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12 December 2020

Obese men respond to cognitive but not to catabolic brain insulin signaling.

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12 December 2020

Variation in the FTO gene locus is associated with cerebrocortical insulin resistance in humans

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12 December 2020

Gonadal hormones determine sensitivity to central leptin and insulin.

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12 December 2020

At last, a weight neutral insulin?

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12 December 2020

Low cerebrospinal fluid insulin levels in obese humans

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12 December 2020

Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects

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12 December 2020

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

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12 December 2020

Diabetes, obesity, and the brain

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12 December 2020

Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study

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12 December 2020

Central insulin action regulates peripheral glucose and fat metabolism in mice

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12 December 2020

Intraventricular insulin and leptin decrease sucrose self-administration in rats.

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12 December 2020

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

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12 December 2020

Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults.

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12 December 2020

Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons

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12 December 2020

Reduced effect of experimental peripheral hyperinsulinemia to elevate cerebrospinal fluid insulin concentrations of obese Zucker rats

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12 December 2020

Hypothalamic insulin signaling is required for inhibition of glucose production

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12 December 2020

Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs

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12 December 2020

Insulin binding to brain capillaries is reduced in genetically obese, hyperinsulinemic Zucker rats

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12 December 2020

Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man

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12 December 2020

Differential sensitivity of men and women to anorexigenic and memory-improving effects of intranasal insulin

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12 December 2020

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport

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12 December 2020

Cognitive dysfunction and diabetes mellitus

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12 December 2020

Relationship between cerebrospinal fluid visfatin (PBEF/Nampt) levels and adiposity in humans

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12 December 2020

Intranasal insulin improves memory in humans: superiority of insulin aspart.

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12 December 2020

The effects of differing insulin levels on the hormonal and metabolic response to equivalent hypoglycemia in normal humans

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12 December 2020

Role of brain insulin receptor in control of body weight and reproduction

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12 December 2020

Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond

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12 December 2020

Central nervous and metabolic effects of intranasally applied leptin

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Quantitative analysis of the olfactory pathway for drug delivery to the brain

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12 December 2020

Supraphysiological hyperinsulinemia acutely increases hypothalamic-pituitary-adrenal secretory activity in humans.

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12 December 2020

Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain

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12 December 2020

Sniffing neuropeptides: a transnasal approach to the human brain

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12 December 2020

Central nervous system control of food intake and body weight

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12 December 2020

Does insulin species modify counterregulatory hormone response to hypoglycemia?

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12 December 2020

Rosiglitazone attenuates the cognitive deficits induced by high fat diet feeding in rats

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12 December 2020

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats

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12 December 2020

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

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12 December 2020

Central obesity and increased risk of dementia more than three decades later

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12 December 2020

Intranasal insulin reduces body fat in men but not in women

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12 December 2020

Intraventricular leptin reduces food intake and body weight of lean rats but not obese Zucker rats.

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12 December 2020

Intracerebroventricular insulin enhances memory in a passive-avoidance task.

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12 December 2020

Improving influence of insulin on cognitive functions in humans

1 reference

12 December 2020

10.1007/S00125-009-1501-X

Identifiers

DOI

1 reference

15 September 2017

1 reference

PubMed ID

19705099