Functional role of HSP90 complexes with endothelial nitric-oxide synthase (eNOS) and calpain on nitric oxide generation in endothelial cells. (Q39953661)

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English	Functional role of HSP90 complexes with endothelial nitric-oxide synthase (eNOS) and calpain on nitric oxide generation in endothelial cells.	scientific article

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11 January 2020

Functional role of HSP90 complexes with endothelial nitric-oxide synthase (eNOS) and calpain on nitric oxide generation in endothelial cells (English)

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11 January 2020

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11 January 2020

Mario Passalacqua

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11 January 2020

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Roberto Stifanese

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11 January 2020

Roberta De Tullio

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11 January 2020

Franca Salamino

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11 January 2020

Sandro Pontremoli

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11 January 2020

Edon Melloni

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5 August 2008

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11 January 2020

Journal of Biological Chemistry

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11 January 2020

29069-29076

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11 January 2020

Geldanamycin, a HSP90 inhibitor, attenuates the hypoxia-induced vascular endothelial growth factor expression in retinal pigment epithelium cells in vitro

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22 September 2017

Mechanistic studies on Hsp90 inhibition by ansamycin derivatives

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22 September 2017

Intelligent biosynthetic nanobiomaterials for hyperthermic combination chemotherapy and thermal drug targeting of HSP90 inhibitor geldanamycin

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22 September 2017

Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.

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22 September 2017

Endothelial function and hypertension

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22 September 2017

Characterization of the calpain/calpastatin system in human hemopoietic cell lines

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22 September 2017

Spatial localization of m-calpain to the plasma membrane by phosphoinositide biphosphate binding during epidermal growth factor receptor-mediated activation

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22 September 2017

Subcellular targeting and trafficking of nitric oxide synthases

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22 September 2017

Caveolins and the regulation of endothelial nitric oxide synthase in the heart

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22 September 2017

Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury

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22 September 2017

Heat shock protein 90 stabilization of ErbB2 expression is disrupted by ATP depletion in myocytes

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22 September 2017

Caveolae and caveolins in the cardiovascular system

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22 September 2017

Protein measurement with the Folin phenol reagent

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22 September 2017

Trafficking and activation of eNOS in epithelial cells

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22 September 2017

The calpain system

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22 September 2017

Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide

1 reference

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22 September 2017

Proteolytic degradation of nitric oxide synthase: effect of inhibitors and role of hsp90-based chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662009

22 September 2017

Relationships between caveolae and eNOS: everything in proximity and the proximity of everything

1 reference

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22 September 2017

Nitric oxide synthases: structure, function and inhibition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662009

22 September 2017

Cellular regulation of endothelial nitric oxide synthase

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22 September 2017

Signal transduction of eNOS activation

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22 September 2017

Targeting and translocation of endothelial nitric oxide synthase

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22 September 2017

Caveolins, liquid-ordered domains, and signal transduction

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22 September 2017

Estradiol induces the calcium-dependent translocation of endothelial nitric oxide synthase.

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22 September 2017

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

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22 September 2017

Structure and physiological function of calpains

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22 September 2017

The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

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22 September 2017

Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity

1 reference

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22 September 2017

Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin

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22 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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22 September 2017

Ovarian expression of cellular Ki-ras p21 varies with physiological status

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22 September 2017

Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme.

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25 September 2017

ATP-binding properties of human Hsp90.

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25 September 2017

A novel role for calpains in the endothelial dysfunction of hyperglycemia

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17 June 2018

Muscular nitric oxide synthase (muNOS) and utrophin

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17 June 2018

Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

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17 June 2018

Changes in intracellular localization of calpastatin during calpain activation

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17 June 2018

The endothelial nitric-oxide synthase-caveolin regulatory cycle

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17 June 2018

Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase

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17 June 2018

Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins.

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17 June 2018

Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90.

1 reference

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20 August 2018

Nitric oxide and superoxide generation from endothelial NOS: modulation by HSP90.

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20 August 2018

H2O2 activation of HSP25/27 protects desmin from calpain proteolysis in rat ventricular myocytes.

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20 August 2018

Regulation of calpain activity in rat brain with altered Ca2+ homeostasis.

1 reference

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20 August 2018

Effects of hsp90 binding inhibitors on sGC-mediated vascular relaxation

1 reference

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20 August 2018

The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins

1 reference

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20 August 2018

eNOS translocation but not eNOS phosphorylation is dependent on intracellular Ca2+ in human atrial myocardium

1 reference

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20 August 2018

Chaperone-dependent regulation of endothelial nitric-oxide synthase intracellular trafficking by the co-chaperone/ubiquitin ligase CHIP.

1 reference

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20 August 2018

Calmodulin-dependent and -independent activation of endothelial nitric-oxide synthase by heat shock protein 90.

1 reference

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20 August 2018

Calpain inhibition decreases the growth rate of mammalian cell colonies

1 reference

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20 August 2018

Ischemia increases detectable endothelial nitric oxide synthase in rat and human myocardium

1 reference

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20 August 2018

Direct evidence of nitric oxide production from bovine aortic endothelial cells using new fluorescence indicators: diaminofluoresceins.

1 reference

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20 August 2018

Animal models of hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS-HSP90 heterocomplex

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic NOS inhibition prevents adverse lung remodeling and pulmonary arterial hypertension in caveolin-1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of heat shock protein 27 protects against ischaemia/reperfusion-induced cardiac dysfunction via stabilization of troponin I and T

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of calpain in hypoxic inhibition of nitric oxide synthase activity in pulmonary endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a monoclonal anti-calpain antibody on responses of stimulated human neutrophils. Evidence for a role for proteolytically modified protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired endothelium-dependent vasodilation in patients with essential hypertension. Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The calcium-dependent protease calpain causes endothelial dysfunction in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial oxidative stress in alcohol-induced hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/18682401

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M803638200

1 reference

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11 January 2020

1 reference

Europe PubMed Central

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11 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18682401%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

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