Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells (Q39955774)

15 September 2017

Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells (English)

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15 September 2017

Xiang-Bo Wan

1

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15 September 2017

Zi-Jie Long

2

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15 September 2017

Min Yan

3

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15 September 2017

Jie Xu

4

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15 September 2017

Liang-Ping Xia

5

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15 September 2017

Li Liu

6

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15 September 2017

Yan Zhao

7

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15 September 2017

Xue-Fei Huang

8

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15 September 2017

Xian-Ren Wang

9

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15 September 2017

Xiao-Feng Zhu

10

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15 September 2017

Ming-Huang Hong

11

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15 September 2017

Quentin Liu

12

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15 September 2017

language of work or name

English

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publication date

30 July 2008

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15 September 2017

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15 September 2017

29

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15 September 2017

1930-1937

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15 September 2017

10

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Aurora kinases link chromosome segregation and cell division to cancer susceptibility

15 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora A, mitotic entry, and spindle bipolarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora-A - a guardian of poles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Hyperexpression of mitogen-activated protein kinase in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Induction of an epithelial to mesenchymal transition in human immortal and malignant keratinocytes by TGF-beta1 involves MAPK, Smad and AP-1 signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

EFA6A enhances glioma cell invasion through ADP ribosylation factor 6/extracellular signal-regulated kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

The epithelial-mesenchymal transition: new insights in signaling, development, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Correcting improper chromosome-spindle attachments during cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Targeting Aurora kinases for the treatment of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

VX-680 inhibits Aurora A and Aurora B kinase activity in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Structure of the kinase domain of an imatinib-resistant Abl mutant in complex with the Aurora kinase inhibitor VX-680.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

The role of epithelial-mesenchymal transition in cancer pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora-A regulation of nuclear factor-kappaB signaling by phosphorylation of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Aurora kinase inhibition downregulates NF-kappaB and sensitises tumour cells to chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

NF-kappaB and IKK as therapeutic targets in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

Ceramide Induces CytochromecRelease from Isolated Mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN176

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGN176

1 reference

15 September 2017

1 reference