Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects (Q39956832)

15 September 2017

Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects (English)

1 reference

15 September 2017

10

1 reference

15 September 2017

M Hall

7

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author name string

A D Michel

1

1 reference

15 September 2017

W C Clay

2

1 reference

15 September 2017

S W Ng

3

1 reference

15 September 2017

S Roman

4

1 reference

15 September 2017

K Thompson

5

1 reference

15 September 2017

J P Condreay

6

1 reference

15 September 2017

J Holbrook

8

1 reference

15 September 2017

D Livermore

9

1 reference

15 September 2017

language of work or name

English

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publication date

28 July 2008

1 reference

British Journal of Pharmacology

15 September 2017

1 reference

15 September 2017

155

1 reference

15 September 2017

5

1 reference

15 September 2017

738-751

1 reference

Negative and positive allosteric modulators of the P2X(7) receptor

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Cloning and pharmacological characterization of the guinea pig P2X7 receptor orthologue

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Agonist potency at P2X7 receptors is modulated by structurally diverse lipids

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Species and response dependent differences in the effects of MAPK inhibitors on P2X(7) receptor function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

The P2X7 receptor: a key player in IL-1 processing and release

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Decavanadate, a P2X receptor antagonist, and its use to study ligand interactions with P2X7 receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

A His-155 to Tyr polymorphism confers gain-of-function to the human P2X7 receptor of human leukemic lymphocytes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Agonists and antagonists acting at P2X7 receptor.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Molecular properties of ATP-gated P2X receptor ion channels

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Recombinant baculoviruses used to study estrogen receptor function in human osteosarcoma cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Molecular physiology of P2X receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Complexities of measuring antagonist potency at P2X(7) receptor orthologs.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Effects of antagonists at the human recombinant P2X7 receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Ionic effects on human recombinant P2X7 receptor function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Direct labelling of the human P2X7 receptor and identification of positive and negative cooperativity of binding

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Guide to Receptors and Channels (GRAC), 3rd edition

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2584934

Integration of PCR fragments at any specific site within cloning vectors without the use of restriction enzymes and DNA ligase

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Amino Acid Residues in the P2X7 Receptor that Mediate Differential Sensitivity to ATP and BzATP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18660826

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJP.2008.306

1 reference

15 September 2017

1 reference

15 September 2017

PubMed publication ID

18660826

1 reference