Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells (Q39958711)

15 September 2017

Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells (English)

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15 September 2017

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15 September 2017

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Margaret A Knowles

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Emma J Chapman

object named as

Emma J Chapman

series ordinal

1

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publication date

1 July 2008

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Molecular Cancer Research

15 September 2017

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15 September 2017

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15 September 2017

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15 September 2017

1154-1168

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PMCID

3437422

describes a project that uses

15 September 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3437422

inferred from PubMed Central ID database lookup

cites work

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Role of polycomb group proteins in stem cell self-renewal and cancer.

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Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

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22 September 2017

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22 September 2017

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22 September 2017

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Activation of peroxisome proliferator-activated receptor-gamma reverses squamous metaplasia and induces transitional differentiation in normal human urothelial cells

22 September 2017

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Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Telomerase: its clinical relevance in the diagnosis of bladder cancer

22 September 2017

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22 September 2017

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The mechanism of the growth-inhibitory effect of coxsackie and adenovirus receptor (CAR) on human bladder cancer: a functional analysis of car protein structure.

22 September 2017

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Necdin acts as a transcriptional repressor that interacts with multiple guanosine clusters

22 September 2017

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The melanoma antigen genes--any clues to their functions in normal tissues?

22 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Reduced expression of PSCA, a member of the LY-6 family of cell surface antigens, in bladder, esophagus, and stomach tumors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Genetic and epigenetic changes in human epithelial cells immortalized by telomerase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Characterization and chromosomal mapping of a human Necdin pseudogene

22 September 2017

1 reference

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Physical and functional interactions of neuronal growth suppressor necdin with p53

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Telomerase activity: a biomarker of cell proliferation, not malignant transformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Differentiation of immortal cells inhibits telomerase activity.

22 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells

22 September 2017

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Wilms tumor in a patient with Prader-Willi syndrome

22 September 2017

1 reference

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Inhibition of growth and enhancement of differentiation of colorectal carcinoma cell lines by MAb MR6 and IL-4.

25 September 2017

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A three-dimensional model of differentiation of immortalized human bronchial epithelial cells

25 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Normal human urothelial cells in vitro: proliferation and induction of stratification.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex

17 June 2018

1 reference

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Nm23/NDP kinases in human male germ cells: role in spermiogenesis and sperm motility?

20 August 2018

1 reference

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Telomerase maintains telomere structure in normal human cells.

20 August 2018

1 reference

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The role of nm23-H1 in the progression of transitional cell bladder cancer.

20 August 2018

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Cytokeratin 20 expression by non-invasive transitional cell carcinomas: potential for distinguishing recurrent from non-recurrent disease.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3437422

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

20 August 2018

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12 December 2020

Prader-Willi syndrome with del(15)(q11,q13) associated with hepatoblastoma

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12 December 2020

Necdin is required for terminal differentiation and survival of primary dorsal root ganglion neurons

1 reference

12 December 2020

Prader-Willi syndrome and intratubular germ cell neoplasia

1 reference

12 December 2020

Suppression of telomerase, reexpression of KAI1, and abrogation of tumorigenicity by nerve growth factor in prostate cancer cell lines

1 reference

12 December 2020

Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features

1 reference

12 December 2020

10.1158/1541-7786.MCR-07-2168

Identifiers

DOI

1 reference

15 September 2017

1 reference

15 September 2017

1 reference

PMCID

3437422