Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action. (Q39958978)

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7 November 2019

title

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action (English)

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7 November 2019

1

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7 November 2019

Manlio Palumbo

6

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7 November 2019

Barbara Gatto

2

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7 November 2019

Ken-ichi Takao

4

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7 November 2019

author name string

Daniele Fabris

3

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7 November 2019

Susumu Kobayashi

5

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7 November 2019

language of work or name

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1 September 2003

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7 November 2019

published in

Nucleic Acids Research

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7 November 2019

volume

31

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7 November 2019

issue

17

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7 November 2019

page(s)

5149-5156

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Structural refinement of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B(1) adduct in a 5'-Cp(AFB)G-3' sequence

7 November 2019

cites work

1 reference

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The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for irreversible stimulation of DNA cleavage

22 September 2017

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Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins.

22 September 2017

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Fourier transform ion cyclotron resonance mass spectrometry: a primer

22 September 2017

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Terpentecin and ECT4B, new family of topoisomerase II targeting antitumor antibiotics produced by Streptomyces: producing organism, fermentation and large scale purification

22 September 2017

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

22 September 2017

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Intercalation of aflatoxin B1 in two oligodeoxynucleotide adducts: comparative 1H NMR analysis of d(ATCAFBGAT).d(ATCGAT) and d(ATAFBGCAT)2.

22 September 2017

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Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure

22 September 2017

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Interactions between twisted DNAs and enzymes: the effects of superhelical turns

25 September 2017

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New diterpenoid antibiotics, spirocardins A and B.

17 June 2018

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UCT4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from Streptomyces sp.

17 June 2018

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A novel DNA adduct, originating from 1,2-epoxy-3,4-butanediol, is the major DNA adduct after exposure to [2,3-(14)C]-1,3-butadiene,[4-(14)C]-1,2-epoxy-3-butane

17 June 2018

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N7-guanine adducts of the epoxy metabolites of 1,3-butadiene in mice lung

20 August 2018

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Kinetics of DNA alkylation, depurination and hydrolysis of anti diol epoxide of benzo(a)pyrene and the effect of cadmium on DNA alkylation.

20 August 2018

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Butadiene monoxide and deoxyguanosine alkylation products at the N7-position.

20 August 2018

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Alkylation of nucleic acids by the antitumor agent COMC

20 August 2018

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12 December 2020

Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3

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12 December 2020

Induction of a heat-stable topoisomerase II-DNA cleavable complex by nonintercalative terpenoides, terpentecin and clerocidin

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12 December 2020

Irreversible and reversible topoisomerase II DNA cleavage stimulated by clerocidin: sequence specificity and structural drug determinants

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12 December 2020

Site-specific synthesis of aflatoxin B(1) adducts within an oligodeoxyribonucleotide containing the human p53 codon 249 sequence

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12 December 2020

Fermentation, isolation and characterization of antibiotic PR-1350

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12 December 2020

Terpentecin and UCT4B, New Family of Topoisomerase II Targeting Antitumor Antibiotics Produced by Streptomyces: Producing Organism, Frementation and Large Scale Purification.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.48.211

UCT-4B, a new antitumor antibiotic with topoisomerase II mediated DNA cleavage activity, from streptomyces sp.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.45.1182

Identifiers

DOI

10.1093/NAR/GKG696

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7 November 2019

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7 November 2019

PubMed publication ID

12930966

1 reference

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