A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines (Q39960419)

15 September 2017

title

A novel arsenical has antitumor activity toward As2O3-resistant and MRP1/ABCC1-overexpressing cell lines (English)

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15 September 2017

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Z Diaz

1

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15 September 2017

K K Mann

2

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15 September 2017

S Marcoux

3

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15 September 2017

M Kourelis

4

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15 September 2017

M Colombo

5

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15 September 2017

P B Komarnitsky

6

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15 September 2017

W H Miller

7

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15 September 2017

language of work or name

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17 July 2008

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15 September 2017

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15 September 2017

volume

22

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15 September 2017

issue

10

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15 September 2017

page(s)

1853-1863

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https://scigraph.springernature.com/pub.10.1038/leu.2008.194

15 September 2017

exact match

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cites work

Treatment of acute promyelocytic leukemia with arsenic trioxide without ATRA and/or chemotherapy

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Arsenic toxicity and potential mechanisms of action

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Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

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Arsenic trioxide (As(2)O(3)) induces apoptosis through activation of Bax in hematopoietic cells

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Elevation of glutathione levels and glutathione S-transferase activity in arsenic-resistant Chinese hamster ovary cells

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Glutathione plays different roles in the induction of the cytotoxic effects of inorganic and organic arsenic compounds in cultured BALB/c 3T3 cells

21 January 2018

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Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines

21 January 2018

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Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.194

JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.194

Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: activation of caspases and down-regulation of Bcl-2 protein

21 January 2018

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Arsenic trioxide inhibits the growth of A498 renal cell carcinoma cells via cell cycle arrest or apoptosis

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History of the development of arsenic derivatives in cancer therapy

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Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes

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A simple fluorescence method for surface antigen phenotyping of lymphocytes undergoing DNA fragmentation

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Trolox selectively enhances arsenic-mediated oxidative stress and apoptosis in APL and other malignant cell lines

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Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

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Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences

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Additive effects of dipyridamole and Trolox in protecting human red cells during photodynamic treatment

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Effective treatment of advanced solid tumors by the combination of arsenic trioxide and L-buthionine-sulfoximine

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Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis

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Resistance of human multidrug resistance-associated protein 1-overexpressing lung tumor cells to the anticancer drug arsenic trioxide.

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Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells

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Toxicity of a trivalent organic arsenic compound, dimethylarsinous glutathione in a rat liver cell line (TRL 1215)

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The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds

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Forced uptake of trivalent and pentavalent methylated and inorganic arsenic and its cyto-/genotoxicity in fibroblasts and hepatoma cells

21 January 2018

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Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity

21 January 2018

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7 January 2021

United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.194

7 January 2021

Vitamin C: a new look

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.194

7 January 2021

The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid

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https://api.crossref.org/works/10.1038%2FLEU.2008.194

7 January 2021

L-S,R-buthionine sulfoximine: historical development and clinical issues

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.194

7 January 2021

Identifiers

DOI

10.1038/LEU.2008.194

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15 September 2017

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