Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells (Q39968250)

16 September 2017

Targeting lipid rafts inhibits protein kinase B by disrupting calcium homeostasis and attenuates malignant properties of melanoma cells (English)

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16 September 2017

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Shlomit Fedida-Metula

1

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16 September 2017

Shira Elhyany

2

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16 September 2017

Sylvia Tsory

3

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16 September 2017

Shraga Segal

4

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16 September 2017

Michal Hershfinkel

5

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16 September 2017

Israel Sekler

6

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16 September 2017

Daniel Fishman

7

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16 September 2017

language of work or name

English

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publication date

25 June 2008

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16 September 2017

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16 September 2017

29

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8

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16 September 2017

1546-1554

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Apoptosis and melanoma chemoresistance

16 September 2017

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Genetic alterations in signaling pathways in melanoma

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Functional and therapeutic significance of Akt deregulation in malignant melanoma.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Deregulated Akt3 activity promotes development of malignant melanoma

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Store-operated calcium channels

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Growth factor-dependent AKT activation and cell migration requires the function of c-K(B)-Ras versus other cellular ras isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

PYK2 mediates anti-apoptotic AKT signaling in response to benzo[a]pyrene diol epoxide in mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Studies on the phosphorylation of protein kinase B by Ca(2+)/calmodulin-dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Elevated levels of cholesterol-rich lipid rafts in cancer cells are correlated with apoptosis sensitivity induced by cholesterol-depleting agents

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Lipid rafts: heterogeneity on the high seas

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Lipid rafts: at a crossroad between cell biology and physics.

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Platelet derived growth factor-BB is a potent mitogen for rat ureteral and human bladder smooth muscle cells: dependence on lipid rafts for cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Lubrol-RAFTs in melanoma cells: a molecular platform for tumor-promoting ephrin-B2-integrin-beta1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Lovastatin-induced apoptosis in human melanoma cell lines

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Loss of plasma membrane phospholipid asymmetry requires raft integrity. Role of transient receptor potential channels and ERK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Genetic evidence supporting caveolae microdomain regulation of calcium entry in endothelial cells

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Free cholesterol alters lipid raft structure and function regulating neutrophil Ca2+ entry and respiratory burst: correlations with calcium channel raft trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Cellular cholesterol controls TRPC3 function: evidence from a novel dominant-negative knockdown strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Alterations in the expression of MHC class I glycoproteins by B16BL6 melanoma cells modulate insulin receptor-regulated signal transduction and augment [correction of augments] resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

The integrity of cholesterol-enriched microdomains is essential for the constitutive high activity of protein kinase B in tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Glial cell line-derived neurotrophic factor increases intracellular calcium concentration. Role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

The blocking of capacitative calcium entry by 2-aminoethyl diphenylborate (2-APB) and carboxyamidotriazole (CAI) inhibits proliferation in Hep G2 and Huh-7 human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Tyrosine kinase modulation of protein kinase C activity regulates G protein-linked Ca2+ signaling in leukemic hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

Antiproliferative effect of methyl-beta-cyclodextrin in vitro and in human tumour xenografted athymic nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN146

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGN146

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16 September 2017

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