Defective MHC class I antigen surface expression promotes cellular survival through elevated ER stress and modulation of p53 function (Q39977171)

16 September 2017

title

Defective MHC class I antigen surface expression promotes cellular survival through elevated ER stress and modulation of p53 function (English)

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16 September 2017

K Sabapathy

1

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16 September 2017

S Y Nam

series ordinal

2

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16 September 2017

publication date

30 May 2008

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Cell Death & Differentiation

16 September 2017

published in

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16 September 2017

volume

15

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16 September 2017

issue

9

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16 September 2017

page(s)

1364-1374

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Nonimmune thyroid destruction results from transgenic overexpression of an allogeneic major histocompatibility complex class I protein

16 September 2017

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Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment

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The role of self-recognition in receptor repertoire development. Members of the Janeway Laboratory

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The regulation and expression of MHC class I genes

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7 January 2021

The optimization of peptide cargo bound to MHC class I molecules by the peptide-loading complex

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MHC class I alleles and their exploration of the antigen-processing machinery

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MHC antigens and tumor escape from immune surveillance

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Re-expression of major histocompatibility complex (MHC) class I molecules on malignant tumor cells and its effect on host-tumor interaction.

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Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells

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7 January 2021

Developmental failure of chimeric embryos expressing high levels of H-2Dd transplantation antigens

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7 January 2021

Dysmyelination in transgenic mice resulting from expression of class I histocompatibility molecules in oligodendrocytes

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7 January 2021

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

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7 January 2021

Inhibition of anti-class I cytotoxicity by anti-class II monoclonal antibodies (MoAb). II. Blocking of anti-class I CTL clones by anti-DR MoAb

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7 January 2021

Surfing the p53 network

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7 January 2021

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

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7 January 2021

Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta

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7 January 2021

Stress induction of GRP78/BiP and its role in cancer.

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7 January 2021

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

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7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

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7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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7 January 2021

Effect of TAP on the generation and intracellular trafficking of peptide-receptive major histocompatibility complex class I molecules

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7 January 2021

Increase in positive selection of CD8+ T cells in TAP1-mutant mice by human beta 2-microglobulin transgene

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7 January 2021

N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma

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7 January 2021

Mutagenesis induced by the tumor microenvironment

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7 January 2021

Expression of MHC class I heavy chain and beta2-microglobulin in rat brainstem motoneurons and nigral dopaminergic neurons

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7 January 2021

Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus

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7 January 2021

Immunosurveillance is active in colorectal cancer as downregulation but not complete loss of MHC class I expression correlates with a poor prognosis.

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7 January 2021

Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions

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7 January 2021

GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer

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7 January 2021

Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

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7 January 2021

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

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7 January 2021

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

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7 January 2021

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

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7 January 2021

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

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7 January 2021

Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis

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7 January 2021

Identifiers

DOI

10.1038/CDD.2008.55

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16 September 2017

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