Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase (Q39982734)

16 September 2017

Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase (English)

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16 September 2017

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hepatocellular carcinoma

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11

Takashi Kumada

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16 September 2017

8

Hidenori Toyoda

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16 September 2017

9

Yuji Kaneoka

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16 September 2017

5

Eisuke Yasuda

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16 September 2017

10

Akihiro Yamaguchi

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16 September 2017

Rie Matsushima-Nishiwaki

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1

object named as

Rie Matsushima-Nishiwaki

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16 September 2017

12

Osamu Kozawa

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16 September 2017

3

Seiji Adachi

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16 September 2017

6

Takahiro Noda

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16 September 2017

Shinji Takai

2

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16 September 2017

Chiho Minamitani

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4

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16 September 2017

Kanefusa Kato

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7

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16 September 2017

language of work or name

English

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publication date

13 May 2008

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Journal of Biological Chemistry

16 September 2017

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16 September 2017

283

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27

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16 September 2017

18852-18860

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Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties

16 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

HSP27 multimerization mediated by phosphorylation-sensitive intermolecular interactions at the amino terminus

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Hepatic tumor necrosis factor signaling and nuclear factor-kappaB: effects on liver homeostasis and beyond.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Redox/ROS regulation of lipopolysaccharide-induced mitogen-activated protein kinase (MAPK) activation and MAPK-mediated TNF-alpha biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Heat shock protein 27 association with the I kappa B kinase complex regulates tumor necrosis factor alpha-induced NF-kappa B activation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Parallel signal processing among mammalian MAPKs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Protein kinase C delta regulates the phosphorylation of heat shock protein 27 in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Theaflavin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-inflammatory effect and modulation of STAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Mitogen-activated protein kinase cascades and regulation of gene expression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

MAPKs: new JNK expands the group

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Regulation of innate immune response by MAP kinase phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Preheating accelerates mitogen-activated protein (MAP) kinase inactivation post-heat shock via a heat shock protein 70-mediated increase in phosphorylated MAP kinase phosphatase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Regulation of proliferation, survival and apoptosis by members of the TNF superfamily

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Downregulation of ERK2 is essential for the inhibition of radiation-induced cell death in HSP25 overexpressed L929 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

HSP25 overexpression attenuates oxidative stress-induced apoptosis: roles of ERK1/2 signaling and manganese superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Small heat shock proteins: a new classification scheme in mammals

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M801301200

Conformational changes resulting from pseudophosphorylation of mammalian small heat shock proteins--a two-hybrid study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

p38 MAP-kinases pathway regulation, function and role in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Redox signaling and the MAP kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Reactive oxygen intermediates in TNF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Role of mechanical and redox stress in activation of mitogen-activated protein kinases in primary cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M801301200

21 January 2018

Identifiers

DOI

10.1074/JBC.M801301200

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16 September 2017

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