Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells (Q39987295)

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English	Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

16 September 2017

Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells (English)

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Europe PubMed Central

PMC publication ID

16 September 2017

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Frederic J Seidler

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Frederic J Seidler

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Europe PubMed Central

PMC publication ID

16 September 2017

Theodore A. Slotkin

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Theodore A Slotkin

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Europe PubMed Central

PMC publication ID

16 September 2017

publication date

5 February 2009

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Europe PubMed Central

PMC publication ID

16 September 2017

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Europe PubMed Central

PMC publication ID

16 September 2017

1263

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Europe PubMed Central

PMC publication ID

16 September 2017

23-32

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Europe PubMed Central

PMC publication ID

16 September 2017

Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670938

22 September 2017

Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670938

22 September 2017

Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro

1 reference

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22 September 2017

Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670938

22 September 2017

Neonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670938

22 September 2017

Developmental diazinon neurotoxicity in rats: later effects on emotional response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670938

22 September 2017

Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon

1 reference

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22 September 2017

Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells

1 reference

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22 September 2017

Exposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamily

1 reference

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Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems

1 reference

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Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel

1 reference

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22 September 2017

Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: chlorpyrifos, chlorpyrifos oxon, and diazinon

1 reference

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1 reference

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Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells

1 reference

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Developmental exposure of rats to chlorpyrifos leads to behavioral alterations in adulthood, involving serotonergic mechanisms and resembling animal models of depression

1 reference

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Convergent effects on cell signaling mechanisms mediate the actions of different neurobehavioral teratogens: alterations in cholinergic regulation of protein kinase C in chick and avian models

1 reference

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Organophosphate toxicology: safety aspects of nonacetylcholinesterase secondary targets

1 reference

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Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates

1 reference

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Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposure

1 reference

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Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling

1 reference

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Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos

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Cell signaling as a target and underlying mechanism for neurobehavioral teratogenesis.

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Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells

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1 reference

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25 September 2017

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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17 June 2018

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Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthion

1 reference

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1 reference

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The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent

1 reference

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20 August 2018

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10.1016/J.BRAINRES.2009.01.049

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Europe PubMed Central

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16 September 2017

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