Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway (Q39992451)

16 September 2017

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway (English)

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16 September 2017

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10

Hugues de Thé

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Nasr Rihab

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object named as

Rihab Nasr

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Valérie Lallemand-Breitenbach

16 September 2017

1

object named as

Valérie Lallemand-Breitenbach

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16 September 2017

Marion Jeanne

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16 September 2017

Shirine Benhenda

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16 September 2017

Ming Lei

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16 September 2017

Laurent Peres

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16 September 2017

Jun Zhou

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16 September 2017

Jun Zhu

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16 September 2017

Brian Raught

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16 September 2017

13 April 2008

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10

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5

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16 September 2017

547-555

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https://scigraph.springernature.com/pub.10.1038/ncb1717

16 September 2017

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cites work

How acute promyelocytic leukaemia revived arsenic

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Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia

21 January 2018

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Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

21 January 2018

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Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

21 January 2018

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

21 January 2018

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JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells

21 January 2018

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Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

21 January 2018

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Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins

21 January 2018

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SUMO-targeted ubiquitin ligases in genome stability.

21 January 2018

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Ubiquitin-dependent proteolytic control of SUMO conjugates

21 January 2018

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The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation

21 January 2018

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The role of PML in tumor suppression

21 January 2018

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Identification of three major sentrinization sites in PML

21 January 2018

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The mechanisms of PML-nuclear body formation

21 January 2018

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Intracellular localization of proteasomal degradation of a viral antigen

21 January 2018

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Identification of the preferential ubiquitination site and ubiquitin-dependent degradation signal of Rpn4

21 January 2018

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Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

21 January 2018

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Transcriptional coregulator SNURF (RNF4) possesses ubiquitin E3 ligase activity

21 January 2018

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Specification of SUMO1- and SUMO2-interacting motifs

21 January 2018

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SUMO-1 promotes association of SNURF (RNF4) with PML nuclear bodies.

21 January 2018

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A sumoylation site in PML/RARA is essential for leukemic transformation.

21 January 2018

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SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

21 January 2018

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Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3.

21 January 2018

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Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

21 January 2018

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Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.

21 January 2018

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PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0

21 January 2018

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Automated identification of SUMOylation sites using mass spectrometry and SUMmOn pattern recognition software.

21 January 2018

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RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB1717

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Dimensions Publication ID

16 September 2017

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