Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53. (Q39994742)

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English	Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

16 September 2017

Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53. (English)

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Europe PubMed Central

PubMed publication ID

16 September 2017

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author name string

Y Matsui

1

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Europe PubMed Central

PubMed publication ID

16 September 2017

J Watanabe

2

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Europe PubMed Central

PubMed publication ID

16 September 2017

M Ikegawa

3

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Europe PubMed Central

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16 September 2017

T Kamoto

4

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Europe PubMed Central

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16 September 2017

O Ogawa

5

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16 September 2017

H Nishiyama

6

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16 September 2017

language of work or name

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publication date

7 April 2008

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Europe PubMed Central

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16 September 2017

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Europe PubMed Central

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16 September 2017

27

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16 September 2017

33

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Europe PubMed Central

PubMed publication ID

16 September 2017

4603-4614

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Europe PubMed Central

PubMed publication ID

16 September 2017

Heterogeneity of cellular proliferation within transitional cell carcinoma: correlation of protein kinase C alpha/betaI expression and activity

1 reference

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

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Post-translational modification of p53 in tumorigenesis

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Two-dimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach

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Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

1 reference

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Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway

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Prevention of graft-versus-host disease by a novel immunosuppressant, PG490-88, through inhibition of alloreactive T cell expansion.

1 reference

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The p53 response: emerging levels of co-factor complexity.

1 reference

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Flavopiridol induces p53 via initial inhibition of Mdm2 and p21 and, independently of p53, sensitizes apoptosis-reluctant cells to tumor necrosis factor

1 reference

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In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

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Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1)

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Antisense targeting protein kinase C alpha and beta1 inhibits gastric carcinogenesis

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Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells

1 reference

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Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells

1 reference

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Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance

1 reference

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Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research

1 reference

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PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells

1 reference

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Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells

1 reference

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Sensitizing effect of galectin-7 in urothelial cancer to cisplatin through the accumulation of intracellular reactive oxygen species

1 reference

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Triptolide, a diterpenoid triepoxide, induces antitumor proliferation via activation of c-Jun NH2-terminal kinase 1 by decreasing phosphatidylinositol 3-kinase activity in human tumor cells

1 reference

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Clinical outcome of a large-scale multi-institutional retrospective study for locally advanced bladder cancer: a survey including 1131 patients treated during 1990-2000 in Japan.

1 reference

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

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Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.

1 reference

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Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation

1 reference

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Evaluation of the mutagenic, cytotoxic, and antitumor potential of triptolide, a highly oxygenated diterpene isolated from Tripterygium wilfordii

1 reference

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Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells

1 reference

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Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells.

1 reference

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Dicoumarol potentiates cisplatin-induced apoptosis mediated by c-Jun N-terminal kinase in p53 wild-type urogenital cancer cell lines

1 reference

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Glycogen Synthase Kinase-3β (GSK3β) Binds to and Promotes the Actions of p53

1 reference

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Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

1 reference

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p21Waf1/Cip1 as a therapeutic target in breast and other cancers

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Triptolide inhibits transcription factor NF-kappaB and induces apoptosis of multiple myeloma cells

1 reference

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p53 and treatment of bladder cancer

1 reference

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Tumor inhibitors. LXXIV. Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii

1 reference

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31 March 2020

Prognostic value of p53 nuclear overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC

1 reference

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Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1)

1 reference

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31 March 2020

Identifiers

10.1038/ONC.2008.89

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 September 2017

ResearchGate publication ID

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