Cellular 5'-3' mRNA exonuclease Xrn1 controls double-stranded RNA accumulation and anti-viral responses. (Q40000006)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766294%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Cellular 5'-3' mRNA exonuclease Xrn1 controls double-stranded RNA accumulation and anti-viral responses (English)

1 reference

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2 March 2020

1

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2 March 2020

author name string

Ian Mohr

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766294%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

publication date

1 March 2015

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2 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766294%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

17

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2 March 2020

page(s)

332-344

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2 March 2020

issue

3

1 reference

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The Structural Basis of Pathogenic Subgenomic Flavivirus RNA (sfRNA) Production

2 March 2020

cites work

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Poxvirus DNA replication

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The virion host shutoff RNase plays a key role in blocking the activation of protein kinase R in cells infected with herpes simplex virus 1.

22 September 2017

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22 September 2017

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A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5' exonucleolytic degradation

22 September 2017

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22 September 2017

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22 September 2017

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Dcp2 decapping protein modulates mRNA stability of the critical interferon regulatory factor (IRF) IRF-7.

22 September 2017

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Coordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1.

22 September 2017

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Viral subversion of the host protein synthesis machinery

22 September 2017

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Viruses and the cellular RNA decay machinery.

22 September 2017

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Coupled 5′ Nucleotide Recognition and Processivity in Xrn1-Mediated mRNA Decay

22 September 2017

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Poliovirus-mediated disruption of cytoplasmic processing bodies

22 September 2017

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An RNA pseudoknot is required for production of yellow fever virus subgenomic RNA by the host nuclease XRN1

22 September 2017

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Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein

22 September 2017

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Interferon-inducible antiviral effectors

22 September 2017

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P bodies, stress granules, and viral life cycles

22 September 2017

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Eukaryotic translation initiation factor 4F architectural alterations accompany translation initiation factor redistribution in poxvirus-infected cells

22 September 2017

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A 5' splice site enhances the recruitment of basal transcription initiation factors in vivo.

22 September 2017

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Colocalization of transcription and translation within cytoplasmic poxvirus factories coordinates viral expression and subjugates host functions

22 September 2017

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Characterization of a second vaccinia virus mRNA-decapping enzyme conserved in poxviruses

22 September 2017

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22 September 2017

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22 September 2017

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Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation

22 September 2017

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Characterization of a vaccinia virus mutant with a deletion of the D10R gene encoding a putative negative regulator of gene expression

22 September 2017

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ARE-mRNA degradation requires the 5'-3' decay pathway.

22 September 2017

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Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome

22 September 2017

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The enzymes and control of eukaryotic mRNA turnover

22 September 2017

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Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycle

22 September 2017

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mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease

22 September 2017

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The herpes simplex virus vhs protein induces endoribonucleolytic cleavage of target RNAs in cell extracts

22 September 2017

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Structural modifications of RNA influence the 5' exoribonucleolytic hydrolysis by XRN1 and HKE1 of Saccharomyces cerevisiae

22 September 2017

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

22 September 2017

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When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

22 September 2017

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A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation

22 September 2017

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Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

22 September 2017

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A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription

22 September 2017

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Identification of the DNA sequences encoding the large subunit of the mRNA-capping enzyme of vaccinia virus

22 September 2017

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Extensive symmetrical transcription of Simian Virus 40 DNA in virus-yielding cells

22 September 2017

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Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs

22 September 2017

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The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

22 September 2017

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Intermolecular duplexes formed from polyadenylylated vaccinia virus RNA.

22 September 2017

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Characterization of a polyriboadenylate polymerase from vaccinia virions

22 September 2017

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RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them

22 September 2017

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Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme.

22 September 2017

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A common strategy for host RNA degradation by divergent viruses

25 September 2017

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Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

17 June 2018

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Modification of the 5' end of mRNA. Association of RNA triphosphatase with the RNA guanylyltransferase-RNA (guanine-7-)methyltransferase complex from vaccinia virus

17 June 2018

1 reference

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Identification of double-stranded virus-specific ribonucleic acid in KB cells infected with type 2 adenovirus

17 June 2018

1 reference

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Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA.

17 June 2018

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Vaccinia virus gene D12L encodes the small subunit of the viral mRNA capping enzyme

17 June 2018

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Poly(A) polymerase and a dissociable polyadenylation stimulatory factor encoded by vaccinia virus

17 June 2018

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Isolation and partial characterization of the poly(A) polymerases from HeLa cells infected with vaccinia virus

17 June 2018

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Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responses

17 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25766294

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification and characterization of a GTP-pyrophosphate exchange activity from vaccinia virions. Association of the GTP-pyrophosphate exchange activity with vaccinia mRNA guanylyltransferase . RNA (guanine-7-)methyltransferase complex (capping enzy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25766294

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Symmetrical in vivo transcription of polyoma DNA and the separation of self-complementary viral and cell RNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25766294

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CHOM.2015.02.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766294%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25766294%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference