Comparative analysis of the antibacterial activity of a novel peptide deformylase inhibitor, GSK1322322. (Q40004818)

16 September 2017

Comparative analysis of the antibacterial activity of a novel peptide deformylase inhibitor, GSK1322322. (English)

1 reference

16 September 2017

Karen O'Dwyer

1

1 reference

16 September 2017

Meredith Hackel

2

1 reference

16 September 2017

Sarah Hightower

3

1 reference

16 September 2017

Daryl Hoban

4

1 reference

16 September 2017

Samuel Bouchillon

5

1 reference

16 September 2017

Donghui Qin

6

1 reference

16 September 2017

Kelly Aubart

7

1 reference

16 September 2017

Magdalena Zalacain

8

1 reference

16 September 2017

Deborah Butler

9

1 reference

16 September 2017

language of work or name

English

0 references

publication date

11 March 2013

1 reference

Antimicrobial Agents and Chemotherapy

16 September 2017

1 reference

16 September 2017

57

1 reference

16 September 2017

5

1 reference

16 September 2017

2333-2342

1 reference

Invasive methicillin-resistant Staphylococcus aureus infections in the United States

16 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Antimicrobial resistance in Haemophilus influenzae

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Peptide deformylase inhibitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Antistaphylococcal activity of LBM415, a new peptide deformylase inhibitor, compared with those of other agents

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Antipneumococcal activity of LBM415, a new peptide deformylase inhibitor, compared with those of other agents

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Characterization of a human peptide deformylase: implications for antibacterial drug design

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Optimisation of antimicrobial therapy using pharmacokinetic and pharmacodynamic parameters

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Processing of the N termini of nascent polypeptide chains requires deformylation prior to methionine removal

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

On the release of the formyl group from nascent protein

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Deformylation and protein biosynthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Activity of LBM415 compared to those of 11 other agents against Haemophilus species

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Changes in the epidemiology of methicillin-resistant Staphylococcus aureus in intensive care units in US hospitals, 1992-2003.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Macrolide-resistant Streptococcus pyogenes in the United States, 2002-2003.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

In vitro antibacterial activity of the peptide deformylase inhibitor BB-83698.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

The Alexander Project 1998-2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Distinctive features of the two classes of eukaryotic peptide deformylases

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Oral antimicrobial susceptibilities of Streptococcus pyogenes recently isolated in five countries.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632952

Hospital and Societal Costs of Antimicrobial‐Resistant Infections in a Chicago Teaching Hospital: Implications for Antibiotic Stewardship

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23478958

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cleavage of the N-terminal formymlethionine residue from a bacteriophage coat protein in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23478958

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.02566-12

1 reference

16 September 2017

1 reference

16 September 2017

1 reference