Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells (Q40009243)

16 September 2017

title

Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells (English)

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16 September 2017

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Robert Evans

1

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16 September 2017

Claudia Naber

2

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16 September 2017

Tara Steffler

3

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16 September 2017

Tamara Checkland

4

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16 September 2017

Jonathan Keats

5

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16 September 2017

Christopher Maxwell

6

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16 September 2017

Troy Perry

7

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16 September 2017

Heidi Chau

8

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16 September 2017

Andrew Belch

9

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16 September 2017

Linda Pilarski

10

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16 September 2017

Tony Reiman

11

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16 September 2017

publication date

1 March 2008

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16 September 2017

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16 September 2017

volume

49

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16 September 2017

issue

3

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16 September 2017

page(s)

559-569

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https://api.crossref.org/works/10.1080%2F10428190701824544

16 September 2017

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Centrosome control of the cell cycle

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190701824544

Cyclin-dependent kinase control of centrosome duplication

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190701824544

A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Dissociating the centrosomal matrix protein AKAP450 from centrioles impairs centriole duplication and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Centrosome aberrations: cause or consequence of cancer progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190701824544

Clinical implication of centrosome amplification in plasma cell neoplasm

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190701824544

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Aurora-A - a guardian of poles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Aurora-A overexpression leads to override of the microtubule-kinetochore attachment checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Aurora-kinase inhibitors as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

Targeting aurora kinases as therapy in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190701824544

10.1080/10428190701824544

21 January 2018

Identifiers

DOI

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16 September 2017

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