Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin (Q40011543)

16 September 2017

Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin (English)

1 reference

16 September 2017

Zhaohui Wang

1

1 reference

16 September 2017

Shannon G Pratts

2

1 reference

16 September 2017

Huiping Zhang

3

1 reference

16 September 2017

Philip J Spencer

4

1 reference

16 September 2017

Ruichao Yu

5

1 reference

16 September 2017

Makoto Tonsho

6

1 reference

16 September 2017

Jigesh A Shah

7

1 reference

16 September 2017

Tatsu Tanabe

8

1 reference

16 September 2017

Harrison R Powell

9

1 reference

16 September 2017

Christene A Huang

10

1 reference

16 September 2017

Joren C Madsen

11

1 reference

16 September 2017

David H Sachs

12

1 reference

16 September 2017

Zhirui Wang

13

1 reference

16 September 2017

19 November 2015

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16 September 2017

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16 September 2017

10

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16 September 2017

4

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16 September 2017

553-565

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Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4(+) cells in vivo

16 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

CCR4 and its ligands: from bench to bedside

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Regulatory T cell ablation causes acute T cell lymphopenia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Expression and characterization of recombinant soluble porcine CD3 ectodomain molecules: mapping the epitope of an anti-porcine CD3 monoclonal antibody 898H2-6-15

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

First experience with the use of a recombinant CD3 immunotoxin as induction therapy in pig-to-primate xenotransplantation: the effect of T-cell depletion on outcome

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

An anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin avoids inhibition by pre-existing antibodies in human blood

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

A fold-back single-chain diabody format enhances the bioactivity of an anti-monkey CD3 recombinant diphtheria toxin-based immunotoxin.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Hematological and serum biochemical values in cynomolgus monkeys anesthetized with ketamine hydrochloride

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4826841

Efficient Treg depletion induces T-cell infiltration and rejection of large tumors

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26643572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLONC.2015.11.008

1 reference

16 September 2017

1 reference

16 September 2017

PubMed publication ID

26643572

1 reference