Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression. (Q40019073)

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7 March 2020

title

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression (English)

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Jenny Mjösberg

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Alex K. Shalek

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Henrik N. Kløverpris

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Wendy A. Burgers

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Evan W Newell

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Thumbi Ndung'u

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Alasdair Leslie

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Samuel W Kazer

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author name string

Jenniffer M Mabuka

4

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Amanda Wellmann

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Zaza Ndhlovu

6

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Marisa C Yadon

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Shepherd Nhamoyebonde

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Maximilian Muenchhoff

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Yannick Simoni

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Frank Andersson

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Warren Kuhn

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Philomena Kamya

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Karyn Pretorius

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Krista Dong

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Amber Moodley

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Victoria Kasprowicz

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Nigel Garrett

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Philip Goulder

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Bruce D Walker

24

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language of work or name

English

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publication date

2 February 2016

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volume

44

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issue

2

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page(s)

391-405

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Inhibition of LTi cell development by CD25 blockade is associated with decreased intrathecal inflammation in multiple sclerosis

7 March 2020

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Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

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Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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Preparation of Single-Cell RNA-Seq Libraries for Next Generation Sequencing

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RORγt⁺ innate lymphoid cells acquire a proinflammatory program upon engagement of the activating receptor NKp44.

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Mucosal innate immune cells regulate both gut homeostasis and intestinal inflammation

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Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

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High-dimensional analysis of the murine myeloid cell system.

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12 December 2020

The immune response during acute HIV-1 infection: clues for vaccine development

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12 December 2020

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

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12 December 2020

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

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12 December 2020

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection

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Lymphoid fibrosis occurs in long-term nonprogressors and persists with antiretroviral therapy but may be reversible with curative interventions

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Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis

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Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.

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Microbial translocation in the pathogenesis of HIV infection and AIDS.

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Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease

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Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

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Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection

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Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

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12 December 2020

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

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A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

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Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity.

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Type 3 innate lymphoid cell depletion is mediated by TLRs in lymphoid tissues of simian immunodeficiency virus-infected macaques

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

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12 December 2020

Human CD117 (cKit)+ innate lymphoid cells have a discrete transcriptional profile at homeostasis and are expanded during filarial infection

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A probabilistic framework for aligning paired-end RNA-seq data

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Enhanced innate type 2 immune response in peripheral blood from patients with asthma

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Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data

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Plasmacytoid dendritic cells promote HIV-1-induced group 3 innate lymphoid cell depletion

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12 December 2020

Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women

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12 December 2020

HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL.

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12 December 2020

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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12 December 2020

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

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Gut inflammation and indoleamine deoxygenase inhibit IL-17 production and promote cytotoxic potential in NKp44+ mucosal NK cells during SIV infection

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Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

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Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells

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12 December 2020

10.1016/J.IMMUNI.2016.01.006

Identifiers

DOI

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