SOCS1 is an inducible negative regulator of IFN lambda induced gene expression in vivo (Q40044687)

16 September 2017

title

SOCS1 is an inducible negative regulator of IFN lambda induced gene expression in vivo (English)

1 reference

16 September 2017

4

1 reference

16 September 2017

Tanja Blumer

1

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16 September 2017

Mairene Coto-Llerena

series ordinal

2

1 reference

16 September 2017

Francois H T Duong

series ordinal

3

1 reference

16 September 2017

language of work or name

English

0 references

publication date

12 September 2017

1 reference

Journal of Biological Chemistry

16 September 2017

published in

1 reference

The Type I Interferonopathies.

16 September 2017

cites work

1 reference

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Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

30 August 2018

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Type III Interferon Induces Distinct SOCS1 Expression Pattern that Contributes to Delayed but Prolonged Activation of Jak/STAT Signaling Pathway: Implications for Treatment Non-Response in HCV Patients

30 August 2018

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Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

30 August 2018

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Dynamic control of type I IFN signalling by an integrated network of negative regulators

30 August 2018

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Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes

30 August 2018

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Selection on a variant associated with improved viral clearance drives local, adaptive pseudogenization of interferon lambda 4 (IFNL4)

30 August 2018

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IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies

30 August 2018

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Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation

30 August 2018

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Suppression of interferon lambda signaling by SOCS-1 results in their excessive production during influenza virus infection

30 August 2018

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Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia

30 August 2018

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Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

30 August 2018

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Dynamic expression profiling of type I and type III interferon-stimulated hepatocytes reveals a stable hierarchy of gene expression

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Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus

30 August 2018

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IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction

30 August 2018

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Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10

30 August 2018

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SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

30 August 2018

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A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

30 August 2018

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30 August 2018

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USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response

30 August 2018

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Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo

30 August 2018

1 reference

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Alpha Interferon Induces Long-Lasting Refractoriness of JAK-STAT Signaling in the Mouse Liver through Induction of USP18/UBP43

30 August 2018

1 reference

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IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo

30 August 2018

1 reference

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Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases

30 August 2018

1 reference

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Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

30 August 2018

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Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes

30 August 2018

1 reference

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Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling

30 August 2018

1 reference

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The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

30 August 2018

1 reference

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Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

30 August 2018

1 reference

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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

30 August 2018

1 reference

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Dysregulation of protein modification by ISG15 results in brain cell injury

30 August 2018

1 reference

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SOCS proteins: negative regulators of cytokine signaling

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

STATs and gene regulation

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

Electrotransfection with "intracellular" buffer.

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

30 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5663890

30 August 2018

Identifiers

DOI

10.1074/JBC.M117.788877

1 reference

16 September 2017

0 references

1 reference