A domain linking the AMPA receptor agonist binding site to the ion pore controls gating and causes lurcher properties when mutated. (Q40055046)

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9 January 2020

title

A domain linking the AMPA receptor agonist binding site to the ion pore controls gating and causes lurcher properties when mutated (English)

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9 January 2020

2

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9 January 2020

author name string

Sabine M Schmid

1

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9 January 2020

Solveig Herrmann

3

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9 January 2020

Markus Werner

4

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9 January 2020

Michael Hollmann

5

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9 January 2020

language of work or name

English

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publication date

1 November 2007

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9 January 2020

published in

Journal of Neuroscience

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9 January 2020

volume

27

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9 January 2020

issue

45

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9 January 2020

page(s)

12230-12241

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NMDAR channel segments forming the extracellular vestibule inferred from the accessibility of substituted cysteines.

9 January 2020

cites work

1 reference

12 December 2020

Investigation by ion channel domain transplantation of rat glutamate receptor subunits, orphan receptors and a putative NMDA receptor subunit

1 reference

12 December 2020

The Lurcher mutation of an alpha-amino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid receptor subunit enhances potency of glutamate and converts an antagonist to an agonist

1 reference

12 December 2020

Mutation of a glutamate receptor motif reveals its role in gating and delta2 receptor channel properties.

1 reference

12 December 2020

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

1 reference

12 December 2020

Mechanism of glutamate receptor desensitization

1 reference

12 December 2020

A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating

1 reference

12 December 2020

Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization.

1 reference

12 December 2020

Pharmacology of delta2 glutamate receptors: effects of pentamidine and protons

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12 December 2020

Structural basis for partial agonist action at ionotropic glutamate receptors

1 reference

12 December 2020

Stargazin differentially controls the trafficking of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate and kainate receptors

1 reference

12 December 2020

Different gating mechanisms in glutamate receptor and K+ channels.

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12 December 2020

Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices.

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12 December 2020

The outer pore of the glutamate receptor channel has 2-fold rotational symmetry

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12 December 2020

Regulation of AMPA receptor gating by ligand binding core dimers

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12 December 2020

Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain.

1 reference

12 December 2020

Effects of the lurcher mutation on GluR1 desensitization and activation kinetics.

1 reference

12 December 2020

Structure and gating of the glutamate receptor ion channel

1 reference

12 December 2020

Molecular determinants of glycine-independent desensitization of NR1/NR2A receptors.

1 reference

12 December 2020

Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3.

1 reference

12 December 2020

Revisiting the postulated "unitary glutamate receptor": electrophysiological and pharmacological analysis in two heterologous expression systems fails to detect evidence for its existence

1 reference

12 December 2020

Molecular mechanism of AMPA receptor noncompetitive antagonism

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12 December 2020

Developmentally regulated, combinatorial RNA processing modulates AMPA receptor biogenesis.

1 reference

12 December 2020

Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor

1 reference

12 December 2020

Conformational restriction blocks glutamate receptor desensitization

1 reference

12 December 2020

Block of kainate receptor desensitization uncovers a key trafficking checkpoint.

1 reference

12 December 2020

Molecular determinants of AMPA receptor subunit assembly

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12 December 2020

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

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12 December 2020

A family of AMPA-selective glutamate receptors

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12 December 2020

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

12 December 2020

Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells

1 reference

12 December 2020

N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1.

1 reference

12 December 2020

Cloned glutamate receptors

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12 December 2020

A single amino acid determines the subunit-specific spider toxin block of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor channels

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12 December 2020

The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family

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12 December 2020

Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene.

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12 December 2020

N-terminal domains in the NR2 subunit control desensitization of NMDA receptors.

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12 December 2020

Glycine-independent NMDA receptor desensitization: localization of structural determinants.

1 reference

12 December 2020

Structure of a glutamate-receptor ligand-binding core in complex with kainate

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12 December 2020

A point mutation in the glutamate binding site blocks desensitization of AMPA receptors

1 reference

12 December 2020

10.1523/JNEUROSCI.3175-07.2007

Identifiers

DOI

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9 January 2020

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