Peroxynitrite formation mediates LPC-induced augmentation of cardiac late sodium currents (Q40062212)

17 September 2017

Peroxynitrite formation mediates LPC-induced augmentation of cardiac late sodium currents (English)

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17 September 2017

Mathieu Gautier

1

1 reference

PubMed ID

17961592

17 September 2017

Henggui Zhang

series ordinal

2

1 reference

PubMed ID

17961592

17 September 2017

Ian M Fearon

series ordinal

3

1 reference

17 September 2017

21 September 2007

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Journal of Molecular and Cellular Cardiology

17 September 2017

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17 September 2017

44

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17 September 2017

2

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17 September 2017

241-251

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From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels

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Nomenclature of voltage-gated sodium channels

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Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.

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Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel

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SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

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Sodium channel variants in heart disease: expanding horizons

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The effects of lysophosphatidylcholine, a toxic metabolite of ischemia, on the components of cardiac excitability in sheep Purkinje fibers

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Accumulation of lysophosphoglycerides with arrhythmogenic properties in ischemic myocardium

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Modulation of cardiac sodium channel gating by lysophosphatidylcholine.

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Ischemic poison lysophosphatidylcholine modifies heart sodium channels gating inducing long-lasting bursts of openings

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Inhibitory effects of palmitoylcarnitine and lysophosphatidylcholine on the sodium current of cardiac ventricular cells

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Rapid onset of lysophosphatidylcholine-induced modification of whole cell cardiac sodium current kinetics

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Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine

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Late Na currents affected by alpha subunit isoform and beta1 subunit co-expression in HEK293 cells

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Lysophosphatidylcholine, a metabolite which accumulates early in myocardium during ischemia, reduces gap junctional coupling in cardiac cells.

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OxLDL enhances L-type Ca2+ currents via lysophosphatidylcholine-induced mitochondrial reactive oxygen species (ROS) production

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Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells

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Lysophosphatidylcholine-induced modulation of Ca(2+)-activated K(+)channels contributes to ROS-dependent proliferation of cultured human endothelial cells

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Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium

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Activation of Ca2+ -activated potassium channels is involved in lysophosphatidylcholine-induced monocyte adhesion to endothelial cells

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Lysophosphatidylcholine enhances superoxide anions production via endothelial NADH/NADPH oxidase

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Insulin and lysophosphatidylcholine synergistically stimulate NO-dependent cGMP production in human endothelial cells

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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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Constitutively active adenosine monophosphate-activated protein kinase regulates voltage-gated sodium channels in ventricular myocytes

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Prevention of postischemic myocardial reperfusion injury by the combined treatment of NCX-4016 and Tempol

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Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids

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Impact of oxidized low density lipoprotein on vascular cells

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Cell signaling by reactive nitrogen and oxygen species in atherosclerosis

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S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein

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Lysophosphatidylcholine activates extracellular signal-regulated kinases 1/2 through reactive oxygen species in rat vascular smooth muscle cells

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Induction of persistent sodium current by exogenous and endogenous nitric oxide

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Nitric oxide modulates cardiac Na(+) channel via protein kinase A and protein kinase G.

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Arrhythmogenic peroxynitrite-induced alterations in mammalian heart contractility and its prevention with quercetin-filled liposomes.

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The effect of lysophosphatidylcholine on the activity of various mitochondrial enzymes

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Benidipine, a dihydropyridine-calcium channel blocker, prevents lysophosphatidylcholine-induced injury and reactive oxygen species production in human aortic endothelial cells

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Hypoxic augmentation of Ca2+ channel currents requires a functional electron transport chain

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Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells

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Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

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Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude

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10.1016/J.YJMCC.2007.09.007

7 January 2021

Identifiers

DOI

1 reference

17 September 2017

1 reference

PubMed ID

17961592