TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling (Q40072195)

17 September 2017

TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling (English)

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17 September 2017

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17 September 2017

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author name string

Genevieve A Secker

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17 September 2017

Edith Sampson

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17 September 2017

Gregory S Schultz

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17 September 2017

Julie T Daniels

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17 September 2017

language of work or name

English

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publication date

7 September 2007

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Experimental Cell Research

17 September 2017

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17 September 2017

314

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17 September 2017

131-142

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Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing.

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Regulation of cell proliferation by Smad proteins

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Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses

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TGF beta-induced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4.

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Non-Smad TGF-beta signals

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Role of p38 MAP kinase in regulation of cell migration and proliferation in healing corneal epithelium

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TGF-beta signal transduction in corneal wound healing as a therapeutic target

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Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair

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Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10

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TGF-beta stimulates primary human skin fibroblast DNA synthesis via an autocrine production of PDGF-related peptides

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Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts

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Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation

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Hammerhead ribozyme targeting connective tissue growth factor mRNA blocks transforming growth factor-beta mediated cell proliferation.

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Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP

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Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring

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Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress.

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Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor

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CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

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Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

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TGF-beta1-induced connective tissue growth factor (CCN2) expression in human renal proximal tubule epithelial cells requires Ras/MEK/ERK and Smad signalling.

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Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

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Immunohistochemical localization of connective tissue growth factor (CTGF) in the mouse embryo between days 7.5 and 14.5 of gestation

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Expression of connective tissue growth factor in human renal fibrosis

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Connective Tissue Growth Factor Expression and Action in Human Corneal Fibroblast Cultures and Rat Corneas after Photorefractive Keratectomy

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Epithelial and connective tissue cell CTGF/CCN2 expression in gingival fibrosis.

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The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix

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Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).

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The MAPK signaling cascade

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p38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades

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Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism

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Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts.

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ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing.

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The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells.

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Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization.

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TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN.

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Homologous peptide of connective tissue growth factor ameliorates epithelial to mesenchymal transition of tubular epithelial cells

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TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

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Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

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Characterization of the limbal epithelial stem cell niche: novel imaging techniques permit in vivo observation and targeted biopsy of limbal epithelial stem cells

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Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells

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Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

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Intrastromal invasion by limbal epithelial cells is mediated by epithelial-mesenchymal transition activated by air exposure

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The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog.

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10.1016/J.YEXCR.2007.09.001

7 January 2021

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DOI

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17 September 2017

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