Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-gamma production of porcine natural killer cells (Q40072681)

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English	Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-gamma production of porcine natural killer cells	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Synergistic effects of IL-2, IL-12 and IL-18 on cytolytic activity, perforin expression and IFN-gamma production of porcine natural killer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

author name string

Masa Pintaric

1

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Wilhelm Gerner

2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

Armin Saalmüller

3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

publication date

25 August 2007

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Europe PubMed Central

PubMed publication ID

17 September 2017

Veterinary Immunology and Immunopathology

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Europe PubMed Central

PubMed publication ID

17 September 2017

121

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Europe PubMed Central

PubMed publication ID

17 September 2017

1-2

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

68-82

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Europe PubMed Central

PubMed publication ID

17 September 2017

Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity.

1 reference

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A monoclonal antibody recognising an epitope associated with pig interleukin-2 receptors

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Natural killer cells in antiviral defense: function and regulation by innate cytokines

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Summary of workshop findings for porcine B-cell markers.

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Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells

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IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18

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Characterisation of the effector cells in antibody-dependent and spontaneous cell-mediated cytotoxicity in swine against target cells infected with transmissible gastroenteritis virus.

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Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers

1 reference

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7 January 2021

The costimulatory effect of IL-18 on the induction of antigen-specific IFN-gamma production by resting T cells is IL-12 dependent and is mediated by up-regulation of the IL-12 receptor beta2 subunit.

1 reference

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Enhancement of porcine natural killer cell activity by recombinant human and murine IL-12

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A triggering structure recognized by G7 monoclonal antibody on porcine lymphocytes and granulocytes

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Establishment and characterization of porcine cytolytic cell lines and clones

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Perforin expression can define CD8 positive lymphocyte subsets in pigs allowing phenotypic and functional analysis of natural killer, cytotoxic T, natural killer T and MHC un-restricted cytotoxic T-cells.

1 reference

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7 January 2021

Porcine interleukin-12 fusion protein and interleukin-18 in combination induce interferon-gamma production in porcine natural killer and T cells

1 reference

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Response of bovine and porcine peripheral blood mononuclear cells to human recombinant interleukin 2(125).

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The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression

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Inducible IL-2 production by dendritic cells revealed by global gene expression analysis.

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A contribution of mouse dendritic cell-derived IL-2 for NK cell activation

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7 January 2021

Characterization of monoclonal antibodies directed against swine leukocytes

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7 January 2021

[gamma][delta] cells: a right time and a right place for a conserved third way of protection

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Interpreting flow cytometry data: a guide for the perplexed

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T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes

1 reference

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7 January 2021

Murine natural killer cell progenitors and their requirements for development

1 reference

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7 January 2021

Natural killer cells utilize both perforin and gamma interferon to regulate murine cytomegalovirus infection in the spleen and liver

1 reference

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7 January 2021

Final steps of natural killer cell maturation: a model for type 1-type 2 differentiation?

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Unravelling natural killer cell function: triggering and inhibitory human NK receptors

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Antitumor effects on mouse melanoma elicited by local secretion of interleukin-12 and their enhancement by treatment with interleukin-18

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7 January 2021

Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens

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Regulation of interferon-gamma production by IL-12 and IL-18.

1 reference

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Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration

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A new "Logicle" display method avoids deceptive effects of logarithmic scaling for low signals and compensated data

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Differentiation between MHC-restricted and non-MHC-restricted porcine cytolytic T lymphocytes

1 reference

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Infection with classical swine fever virus: effects on phenotype and immune responsiveness of porcine T lymphocytes

1 reference

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Analyses of monoclonal antibodies reacting with porcine CD3: results from the Second International Swine CD Workshop

1 reference

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Design of a flow cytometric assay for the determination of natural killer and cytotoxic T-lymphocyte activity in human and in different animal species

1 reference

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Host environment as a modulating factor of swine natural killer cell activity.

1 reference

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Resting porcine T lymphocytes expressing class II major histocompatibility antigen

1 reference

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T-helper cells from naive to committed.

1 reference

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Reciprocal regulation between natural killer cells and autoreactive T cells

1 reference

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

1 reference

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Perforin and interferon-gamma activities independently control tumor initiation, growth, and metastasis.

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Porcine gammadelta T cells: possible roles on the innate and adaptive immune responses following virus infection.

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Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

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Functional significance of the perforin/granzyme cell death pathway

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Immunology. A pathogen receptor on natural killer cells

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Report on the analyses of mAb reactive with porcine CD8 for the second international swine CD workshop.

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Analyses of monoclonal antibodies reactive with porcine CD44 and CD45

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Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells.

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Identifiers

10.1016/J.VETIMM.2007.08.009

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

ResearchGate publication ID

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