Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization. (Q40082395)

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scientific article published on 11 September 2007

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English	Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization.	scientific article published on 11 September 2007

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scholarly article

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7 January 2020

Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization (English)

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alternative mRNA splicing, via spliceosome

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based on heuristic

inferred from title

4

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Isabelle Goulet

1

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Gabrielle Gauvin

2

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Sophie Boisvenue

3

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11 September 2007

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Journal of Biological Chemistry

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33009-33021

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7 January 2020

Arginine methylation an emerging regulator of protein function

1 reference

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21 January 2018

PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells

1 reference

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21 January 2018

Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1

1 reference

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Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains

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Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src

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In vivo and in vitro arginine methylation of RNA-binding proteins

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The RGG domain in hnRNP A2 affects subcellular localization

1 reference

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The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase

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Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway

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Interaction of PRMT1 with BTG/TOB proteins in cell signalling: molecular analysis and functional aspects

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The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

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A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation

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TIS21 (/BTG2/PC3) as a link between ageing and cancer: cell cycle regulator and endogenous cell death molecule.

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FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1

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hCAF1, a new regulator of PRMT1-dependent arginine methylation

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21 January 2018

PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation

1 reference

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21 January 2018

PRMT3 is a distinct member of the protein arginine N-methyltransferase family. Conferral of substrate specificity by a zinc-finger domain.

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21 January 2018

The structure and oligomerization of the yeast arginine methyltransferase, Hmt1

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Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2)

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21 January 2018

Genomic organization, physical mapping, and expression analysis of the human protein arginine methyltransferase 1 gene

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21 January 2018

Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable

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21 January 2018

A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines

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21 January 2018

A proteomic analysis of arginine-methylated protein complexes

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21 January 2018

WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif

1 reference

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21 January 2018

Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control.

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21 January 2018

A system for stable expression of short interfering RNAs in mammalian cells

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21 January 2018

Protein arginine methyltransferase I: substrate specificity and role in hnRNP assembly

1 reference

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21 January 2018

Structure of the Predominant Protein Arginine Methyltransferase PRMT1 and Analysis of Its Binding to Substrate Peptides

1 reference

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21 January 2018

Promoter2.0: for the recognition of PolII promoter sequences.

1 reference

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21 January 2018

DBTSS: DataBase of human Transcriptional Start Sites and full-length cDNAs

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Application of a time-delay neural network to promoter annotation in the Drosophila melanogaster genome

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21 January 2018

Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge

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21 January 2018

A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro

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21 January 2018

Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns

1 reference

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21 January 2018

Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites

1 reference

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21 January 2018

Coilin methylation regulates nuclear body formation

1 reference

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21 January 2018

Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.

1 reference

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21 January 2018

The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies

1 reference

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21 January 2018

Spliceosome Sm proteins D1, D3, and B/B' are asymmetrically dimethylated at arginine residues in the nucleus

1 reference

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21 January 2018

The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins

1 reference

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21 January 2018

Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln

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21 January 2018

The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.

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21 January 2018

Identifying and quantifying in vivo methylation sites by heavy methyl SILAC

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21 January 2018

Analysis and prediction of leucine-rich nuclear export signals

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Nucleocytoplasmic transport: taking an inventory

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Transport between the cell nucleus and the cytoplasm

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21 January 2018

Leucine-rich nuclear-export signals: born to be weak

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21 January 2018

Nonsense-mediated mRNA decay in mammals

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21 January 2018

Alternatively spliced T-cell receptor transcripts are up-regulated in response to disruption of either splicing elements or reading frame.

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21 January 2018

Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function

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21 January 2018

Regulation of gene expression by alternative untranslated regions

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21 January 2018

Immunohistochemical and western analyses of protein arginine N-methyltransferase 3 in the mouse brain.

1 reference

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21 January 2018

Crystal structure of the conserved core of protein arginine methyltransferase PRMT3

1 reference

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21 January 2018

Protein-arginine methyltransferase I, the predominant protein-arginine methyltransferase in cells, interacts with and is regulated by interleukin enhancer-binding factor 3

1 reference

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21 January 2018

The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity

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21 January 2018

Arginine methylation of RNA helicase a determines its subcellular localization

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21 January 2018

Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation

1 reference

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21 January 2018

Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1

1 reference

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21 January 2018

A protein-arginine methyltransferase binds to the intracytoplasmic domain of the IFNAR1 chain in the type I interferon receptor

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21 January 2018

Involvement of receptor-bound protein methyltransferase PRMT1 in antiviral and antiproliferative effects of type I interferons

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21 January 2018

DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo

1 reference

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21 January 2018

The tumor suppressor DAL-1/4.1B modulates protein arginine N-methyltransferase 5 activity in a substrate-specific manner.

1 reference

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21 January 2018

The tumor suppressor DAL-1/4.1B and protein methylation cooperate in inducing apoptosis in MCF-7 breast cancer cells

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21 January 2018

Protein arginine methyltransferases: guardians of the Arg?

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Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status

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21 January 2018

Involvement of arginine methyltransferase CARM1 in androgen receptor function and prostate cancer cell viability

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In vivo posttranslational modifications of the high mobility group A1a proteins in breast cancer cells of differing metastatic potential

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The AT-hook of the chromatin architectural transcription factor high mobility group A1a is arginine-methylated by protein arginine methyltransferase 6

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21 January 2018

Coactivator-associated arginine methyltransferase 1, CARM1, affects pre-mRNA splicing in an isoform-specific manner

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10.1074/JBC.M704349200

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7 January 2020

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Europe PubMed Central

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7 January 2020

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