Appearance of antidepressant-like effect by sildenafil in rats after central muscarinic receptor blockade: evidence from behavioural and neuro-receptor studies. (Q40083764)

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scientific article published on 7 September 2007

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English	Appearance of antidepressant-like effect by sildenafil in rats after central muscarinic receptor blockade: evidence from behavioural and neuro-receptor studies.	scientific article published on 7 September 2007

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6 January 2020

Appearance of antidepressant-like effect by sildenafil in rats after central muscarinic receptor blockade: evidence from behavioural and neuro-receptor studies (English)

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6 January 2020

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6 January 2020

Christiaan B Brink

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6 January 2020

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J D Clapton

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6 January 2020

B E Eagar

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6 January 2020

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7 September 2007

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6 January 2020

Journal of Neural Transmission

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6 January 2020

115

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6 January 2020

1

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6 January 2020

117-125

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6 January 2020

The adrenergic-cholinergic imbalance hypothesis of depression: a review and a perspective

1 reference

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21 January 2018

Postmortem distribution of sildenafil in histological material

1 reference

https://api.crossref.org/works/10.1007%2FS00702-007-0806-5

21 January 2018

Influence of sildenafil on central dopamine-mediated behaviour in male rats

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https://pubmed.ncbi.nlm.nih.gov/17823768

12 December 2020

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Increased hippocampal nitric oxide synthase activity and stress responsiveness after imipramine discontinuation: role of 5HT 2A/C-receptors

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Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats

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Nucleus accumbens muscarinic receptors in the control of behavioral depression: antidepressant-like effects of local M1 antagonist in the Porsolt swim test

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Acute stress facilitates long-lasting changes in cholinergic gene expression

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In the rat forced swimming test, NA-system mediated interactions may prevent the 5-HT properties of some subacute antidepressant treatments being expressed

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Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression

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Nicotinic acetylcholine receptors as targets for antidepressants.

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12 December 2020

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mRNA expression patterns of the cGMP‐hydrolyzing phosphodiesterases types 2, 5, and 9 during development of the rat brain

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Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice

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Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors

1 reference

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12 December 2020

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In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs

1 reference

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12 December 2020

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Neurologic, psychological, and aggressive disturbances with sildenafil

1 reference

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12 December 2020

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Dose-dependent down-regulation of beta-adrenergic receptors after chronic intravenous infusion of antidepressants

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Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity

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Ontogeny of muscarinic cholinergic supersensitivity in the Flinders Sensitive Line rat.

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12 December 2020

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Reduction of cGMP and nitric oxide has antidepressant-like effects in the forced swimming test in rats

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12 December 2020

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Efficacy of sildenafil citrate (Viagra) for the treatment of erectile dysfunction in men in remission from depression

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12 December 2020

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Idazoxan and 8-OH-DPAT modify the behavioral effects induced by either NA, or 5-HT, or dual NA/5-HT reuptake inhibition in the rat forced swimming test

1 reference

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12 December 2020

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Muscarinic receptor sequestration in SH-SY5Y neuroblastoma cells is inhibited when clathrin distribution is perturbed.

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Serum anticholinergic activity and behavior following atropine sulfate administration in the rat.

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Human brain receptor alterations in suicide victims

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Phosphodiesterase inhibition by sildenafil citrate attenuates the learning impairment induced by blockade of cholinergic muscarinic receptors in rats

1 reference

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Evidence that lithium induces a glutamatergic: nitric oxide-mediated response in rat brain

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Behavioural despair in rats: A new model sensitive to antidepressant treatments

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Involvement of the NMDA receptor, NO-cyclic GMP and nuclear factor K-beta in an animal model of repeated trauma

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Alteration of decreased plasma NO metabolites and platelet NO synthase activity by paroxetine in depressed patients

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Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response

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Nitric oxide as modulator of neuronal function

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Anxiolytic and antidepressant properties of methylene blue in animal models

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Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test

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Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat.

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Muscarinic receptor subtypes in human neuroblastoma cell lines SH-SY5Y and IMR-32 as determined by receptor binding, Ca++ mobilization and northern blotting

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Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice.

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Detection of serotonergic and noradrenergic antidepressants in the rat forced swimming test: the effects of water depth

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Glutamate and depression: clinical and preclinical studies

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Localization and characterization of cGMP-immunoreactive structures in rat brain slices after NO-dependent and NO-independent stimulation of soluble guanylyl cyclase.

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Lithium modulation of cortical cyclic nucleotides: evidence for the Yin-Yang hypothesis

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Nitric oxide synthase inhibitors have antidepressant-like properties in mice. 1. Acute treatments are active in the forced swim test

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NMDA receptor involvement in imipramine withdrawal-associated effects on swim stress, GABA levels and NMDA receptor binding in rat hippocampus

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12 December 2020

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Effects of myo-inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells

1 reference

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Variability of chronic antidepressant treatments on beta-adrenergic receptor sites

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Nitric oxide synthase-containing neurons in the human hypothalamus: reduced number of immunoreactive cells in the paraventricular nucleus of depressive patients and schizophrenics

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Cholinergic mechanisms in depression

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Cholinergic-NO-cGMP mediation of sildenafil-induced antinociception.

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