Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. (Q40084257)

17 September 2017

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. (English)

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COP1, E3 ubiquitin ligase

17 September 2017

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CREB regulated transcription coactivator 2

GOA release 2020-03-11

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GOA release 2020-03-11

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Renaud Dentin

1

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17 September 2017

Yi Liu

2

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17 September 2017

Seung-Hoi Koo

3

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17 September 2017

Susan Hedrick

4

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17 September 2017

Thomas Vargas

5

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17 September 2017

Jose Heredia

6

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17 September 2017

John Yates

7

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17 September 2017

Marc Montminy

8

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17 September 2017

language of work or name

English

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publication date

5 September 2007

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17 September 2017

4

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inferred from page(s)

published in

Nature

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17 September 2017

449

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17 September 2017

7160

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17 September 2017

366-369

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https://scigraph.springernature.com/pub.10.1038/nature06128

17 September 2017

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cites work

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

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https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

More TORC for the gluconeogenic engine

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https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Regulatable promoters for use in gene therapy applications: modification of the 5'-flanking region of the CFTR gene with multiple cAMP response elements to support basal, low-level gene expression that can be upregulated by exogenous agents that rai

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Identification of a structural motif that confers specific interaction with the WD40 repeat domain of Arabidopsis COP1.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

The ubiquitin ligase COP1 is a critical negative regulator of p53

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https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

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https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Shotgun identification of protein modifications from protein complexes and lens tissue

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https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

TORCs: transducers of regulated CREB activity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06128

7 January 2021

Identifiers

DOI

10.1038/NATURE06128

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Dimensions Publication ID

17 September 2017

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