The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing. (Q40088699)

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4 January 2020

title

The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing (English)

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4 January 2020

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4

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4 January 2020

author name string

M Nuytten

1

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4 January 2020

L Beke

2

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4 January 2020

A Van Eynde

3

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4 January 2020

M Beullens

5

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4 January 2020

P Van Hummelen

6

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4 January 2020

F Fuks

7

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4 January 2020

M Bollen

8

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4 January 2020

language of work or name

English

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publication date

3 September 2007

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4 January 2020

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4 January 2020

volume

27

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4 January 2020

issue

10

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4 January 2020

page(s)

1449-1460

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The gene encoding the prostatic tumor suppressor PSP94 is a target for repression by the Polycomb group protein EZH2.

4 January 2020

cites work

1 reference

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The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly

21 January 2018

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NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry

21 January 2018

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Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1

21 January 2018

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

21 January 2018

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

21 January 2018

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

21 January 2018

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The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.

21 January 2018

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SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

21 January 2018

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Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

21 January 2018

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Functional diversity of protein phosphatase-1, a cellular economizer and reset button

21 January 2018

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Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution.

21 January 2018

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Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3

21 January 2018

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Polycomb silencing blocks transcription initiation.

21 January 2018

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Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers

21 January 2018

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Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1

21 January 2018

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Mapping of the RNA-binding and endoribonuclease domains of NIPP1, a nuclear targeting subunit of protein phosphatase 1

21 January 2018

1 reference

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The protein phosphatase-1 (PP1) regulator, nuclear inhibitor of PP1 (NIPP1), interacts with the polycomb group protein, embryonic ectoderm development (EED), and functions as a transcriptional repressor

21 January 2018

1 reference

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Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

21 January 2018

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

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Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

21 January 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

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Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family

21 January 2018

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The polycomb-group gene Ezh2 is required for early mouse development

21 January 2018

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The polycomb group protein Suz12 is required for embryonic stem cell differentiation

21 January 2018

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Role of histone H3 lysine 27 methylation in X inactivation

21 January 2018

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Polycomb comes of age: genome-wide profiling of target sites

21 January 2018

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Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins

21 January 2018

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Polycomb silencing mechanisms and the management of genomic programmes

21 January 2018

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Stabilization of chromatin structure by PRC1, a Polycomb complex

21 January 2018

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Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.

21 January 2018

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Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes

21 January 2018

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Polycomb silencers control cell fate, development and cancer

21 January 2018

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Suz12 binds to silenced regions of the genome in a cell-type-specific manner

21 January 2018

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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

21 January 2018

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Significance analysis of microarrays applied to the ionizing radiation response

21 January 2018

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The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation

21 January 2018

1 reference

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Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma.

21 January 2018

1 reference

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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Inhibition of spliceosome assembly by the cell cycle-regulated protein kinase MELK and involvement of splicing factor NIPP1

21 January 2018

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The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells

21 January 2018

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NIPP-1, a nuclear inhibitory subunit of protein phosphatase-1, has RNA-binding properties

21 January 2018

1 reference

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7 January 2021

Mapping of the RNA-binding and endoribonuclease domains of NIPP1, a nuclear targeting subunit of protein phosphatase 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210774

7 January 2021

Genomic approaches that aid in the identification of transcription factor target genes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210774

7 January 2021

The transcriptional repression by NIPP1 is mediated by Polycomb group proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210774

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210774

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17724462%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 January 2020

1015654200

0 references

1 reference