Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms. (Q40107095)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

author name string

Joell J Gills

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

S Sianna Castillo

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Chunyu Zhang

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Pavel A Petukhov

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Regan M Memmott

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Melinda Hollingshead

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Jiahuai Han

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Alan P Kozikowski

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Phillip A Dennis

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

language of work or name

0 references

publication date

13 July 2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Journal of Biological Chemistry

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

282

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

37

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

27020-27029

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

MAP kinase modules: many roads home.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

The p38 MAP kinase pathway and its biological function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Activation and signaling of the p38 MAP kinase pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

p38 MAP kinase: a convergence point in cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Role of the p38 MAPK pathway in cisplatin-based therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Structural basis of inhibitor selectivity in MAP kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

The specificities of protein kinase inhibitors: an update

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Feedback control of the protein kinase TAK1 by SAPK2a/p38

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Active mutants of the human p38alpha mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

The p38 pathway provides negative feedback for Ras proliferative signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

p38 MAPK mediates gamma-irradiation-induced endothelial cell apoptosis, and vascular endothelial growth factor protects endothelial cells through the phosphoinositide 3-kinase-Akt-Bcl-2 pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

p38 MAP kinase--a molecular switch between VEGF-induced angiogenesis and vascular hyperpermeability.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Targeting signal transduction as a strategy to treat inflammatory diseases.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701108200

21 January 2018

Identifiers

10.1074/JBC.M701108200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

release_yzvct6baebblvom3uffbiyhfvu

1 reference

https://api.fatcat.wiki/v0/release/yzvct6baebblvom3uffbiyhfvu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17631503%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40107095&oldid=1844266355"