The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro (Q40120595)

17 September 2017

title

The C-terminal region of the proprotein convertase 1/3 (PC1/3) exerts a bimodal regulation of the enzyme activity in vitro (English)

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17 September 2017

3

Jimmy D Dikeakos

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17 September 2017

Nadia Rabah

1

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17 September 2017

Dany Gauthier

series ordinal

2

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17 September 2017

Timothy L Reudelhuber

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4

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17 September 2017

Claude Lazure

series ordinal

5

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17 September 2017

language of work or name

English

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publication date

12 June 2007

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17 September 2017

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17 September 2017

volume

274

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17 September 2017

issue

13

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17 September 2017

page(s)

3482-3491

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Biosynthesis of peptide hormones derived from precursor sequences

17 September 2017

cites work

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Autoproteolytic activation of the mouse prohormone convertase mPC1.

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Proprotein convertase PC1/3-related peptides are potent slow tight-binding inhibitors of murine PC1/3 and Hfurin

21 January 2018

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Single amino acid substitution in the PC1/3 propeptide can induce significant modifications of its inhibitory profile toward its cognate enzyme

21 January 2018

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Molecular characterization, enzymatic analysis, and purification of murine proprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells

21 January 2018

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The integrity of the RRGDL sequence of the proprotein convertase PC1 is critical for its zymogen and C-terminal processing and for its cellular trafficking

21 January 2018

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The Arg617-Arg618 cleavage site in the C-terminal domain of PC1 plays a major role in the processing and targeting of the enzyme within the regulated secretory pathway

21 January 2018

1 reference

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Association of prohormone convertase 3 with membrane lipid rafts.

21 January 2018

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A predicted alpha -helix mediates targeting of the proprotein convertase PC1 to the regulated secretory pathway

21 January 2018

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Modulation of secretory granule-targeting efficiency by cis and trans compounding of sorting signals

21 January 2018

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Two activation states of the prohormone convertase PC1 in the secretory pathway

21 January 2018

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Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes

21 January 2018

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The peptidase zymogen proregions: nature's way of preventing undesired activation and proteolysis

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Function of the signal peptide and N- and C-terminal propeptides in the leucine aminopeptidase from Aeromonas proteolytica

21 January 2018

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Sequential autolytic processing activates the zymogen of Arg-gingipain

21 January 2018

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Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo

21 January 2018

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Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes

21 January 2018

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In vitro cleavage of internally quenched fluorogenic human proparathyroid hormone and proparathyroid-related peptide substrates by furin. Generation of a potent inhibitor

21 January 2018

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Barley serine proteinase inhibitor 2-derived cyclic peptides as potent and selective inhibitors of convertases PC1/3 and furin

21 January 2018

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Role of two chloride-binding sites in functioning of testicular angiotensin-converting enzyme.

21 January 2018

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Activation and inhibition of rubber transferases by metal cofactors and pyrophosphate substrates

21 January 2018

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Zinc ions trigger conformational change and oligomerization of hepatitis B virus capsid protein

21 January 2018

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Activation of human liver 3 alpha-hydroxysteroid dehydrogenase by sulphobromophthalein

21 January 2018

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Specific modulation of Kex2/furin family proteases by potassium

21 January 2018

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Identification and characterization of spodoptera frugiperda furin: a thermostable subtilisin-like endopeptidase

21 January 2018

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The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study

21 January 2018

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Structural elements that direct specific processing of different mammalian subtilisin-like prohormone convertases

21 January 2018

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Structure-function analysis of the prosegment of the proprotein convertase PC5A.

21 January 2018

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Recycling of furin from the plasma membrane. Functional importance of the cytoplasmic tail sorting signals and interaction with the AP-2 adaptor medium chain subunit

21 January 2018

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Importance of the carboxyl-terminal FTSL motif of membrane cofactor protein for basolateral sorting and endocytosis. Positive and negative modulation by signals inside and outside the cytoplasmic tail

21 January 2018

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The PC6B cytoplasmic domain contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments

21 January 2018

1 reference

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The prohormone processing enzyme PC3 is a lipid raft-associated transmembrane protein

21 January 2018

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The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3

21 January 2018

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Improved PC1/3 production through recombinant expression in insect cells and larvae

21 January 2018

1 reference

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Proprotein Convertase PC3 Is Not a Transmembrane Protein†

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05883.X

10.1111/J.1742-4658.2007.05883.X

21 January 2018

Identifiers

DOI

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17 September 2017

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