ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136. (Q40120813)

17 September 2017

title

ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136. (English)

1 reference

17 September 2017

Aird RE

1

1 reference

17 September 2017

Thomson M

2

1 reference

17 September 2017

Macpherson JS

3

1 reference

17 September 2017

Thurston DE

4

1 reference

17 September 2017

Jodrell DI

5

1 reference

17 September 2017

Guichard SM

6

1 reference

17 September 2017

publication date

12 June 2007

1 reference

The Pharmacogenomics Journal

17 September 2017

published in

1 reference

17 September 2017

volume

8

1 reference

17 September 2017

issue

4

1 reference

17 September 2017

page(s)

289-296

1 reference

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

17 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Expression of a multidrug-resistance gene in human tumors and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 2: efficacy evaluations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

The novel sequence-specific DNA cross-linking agent SJG-136 (NSC 694501) has potent and selective in vitro cytotoxicity in human B-cell chronic lymphocytic leukemia cells with evidence of a p53-independent mechanism of cell kill

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Influence of P-glycoprotein expression on in vitro cytotoxicity and in vivo antitumour activity of the novel pyrrolobenzodiazepine dimer SJG-136.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

A bicistronic retroviral vector for protecting hematopoietic cells against antifolates and P-glycoprotein effluxed drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Haploview: analysis and visualization of LD and haplotype maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

New colorimetric cytotoxicity assay for anticancer-drug screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

7 January 2021

The Effect of CYP3A5 and MDR1 Polymorphic Expression on Cyclosporine Oral Disposition in Renal Transplant Patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

7 January 2021

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

7 January 2021

MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

7 January 2021

Concordance of pharmacogenetic markers in germline and colorectal tumor DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.TPJ.6500465

7 January 2021

Identifiers

DOI

10.1038/SJ.TPJ.6500465

1 reference

Dimensions Publication ID

17 September 2017

1048759175

0 references

1 reference