Replication-competent adenovirus-mediated suicide gene therapy with radiation in a preclinical model of pancreatic cancer (Q40123376)

17 September 2017

title

Replication-competent adenovirus-mediated suicide gene therapy with radiation in a preclinical model of pancreatic cancer (English)

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adaptive radiation therapy

17 September 2017

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Svend O Freytag

1

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17 September 2017

Kenneth N Barton

2

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Stephen L Brown

3

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Vinod Narra

4

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Yingshu Zhang

5

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Don Tyson

6

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Colleen Nall

7

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Mei Lu

8

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Munther Ajlouni

9

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Benjamin Movsas

10

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Jae Ho Kim

11

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publication date

12 June 2007

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17 September 2017

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17 September 2017

volume

15

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issue

9

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page(s)

1600-1606

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Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial

17 September 2017

cites work

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A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

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Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization

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Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

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Second-generation replication-competent oncolytic adenovirus armed with improved suicide genes and ADP gene demonstrates greater efficacy without increased toxicity

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Five-year follow-up of trial of replication-competent adenovirus-mediated suicide gene therapy for treatment of prostate cancer

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Phase I trial of replication-competent adenovirus-mediated suicide gene therapy combined with IMRT for prostate cancer

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Positron emission tomography imaging of adenoviral-mediated transgene expression in liver cancer patients

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

GENIS: gene expression of sodium iodide symporter for noninvasive imaging of gene therapy vectors and quantification of gene expression in vivo

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Gastrointestinal Tumor Study Group

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

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Preoperative chemoradiation strategies for localized adenocarcinoma of the pancreas

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Selective enhancement of radiation response of herpes simplex virus thymidine kinase transduced 9L gliosarcoma cells in vitro and in vivo by antiviral agents

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Evaluation of the biodistribution, persistence, toxicity, and potential of germ-line transmission of a replication-competent human adenovirus following intraprostatic administration in the mouse

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300212

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300212

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17 September 2017

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