Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration (Q40134433)

17 September 2017

Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration (English)

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17 September 2017

Lilly Y W Bourguignon

series ordinal

1

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17 September 2017

Eli Gilad

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2

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17 September 2017

Karine Peyrollier

series ordinal

3

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17 September 2017

language of work or name

English

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publication date

10 May 2007

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Journal of Biological Chemistry

17 September 2017

16

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based on heuristic

inferred from page(s)

published in

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17 September 2017

282

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17 September 2017

27

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17 September 2017

19426-19441

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Hyaluronan: a multifunctional, megaDalton, stealth molecule

17 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan in morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Signaling properties of hyaluronan receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Mammalian hyaluronan synthases: investigation of functional relationships in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Functional cloning of the cDNA for a human hyaluronan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Molecular identification of a putative human hyaluronan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Neu and its ligands: from an oncogene to neural factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Aberrant expression of the c-erbB-2/neu protooncogene in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan-CD44 interaction with neural Wiskott-Aldrich syndrome protein (N-WASP) promotes actin polymerization and ErbB2 activation leading to beta-catenin nuclear translocation, transcriptional up-regulation, and cell migration in ovarian tumor ce

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Identification of heregulin, a specific activator of p185erbB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

The ErbB signaling network: receptor heterodimerization in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Inhibition of the MAP kinase cascade blocks heregulin-induced cell cycle progression in T-47D human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

An agarose gel electrophoretic method for analysis of hyaluronan molecular weight distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan-CD44 interaction with leukemia-associated RhoGEF and epidermal growth factor receptor promotes Rho/Ras co-activation, phospholipase C epsilon-Ca2+ signaling, and cytoskeleton modification in head and neck squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Phospholipid dependence and liposome reconstitution of purified hyaluronan synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan-CD44 interaction with Rac1-dependent protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca(2+) signaling, and cortactin-cytoskeleton function leading to keratinocyte adhesion and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Epidermal growth factor activates hyaluronan synthase 2 in epidermal keratinocytes and increases pericellular and intracellular hyaluronan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan enters keratinocytes by a novel endocytic route for catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Recombinant human hyaluronan synthase 3 is phosphorylated in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Biology of the p21-activated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Multiple roles for Cdc42 in cell regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Filamins as integrators of cell mechanics and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

'Piggy-back' transport of Xenopus hyaluronan synthase (XHAS1) via the secretory pathway to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Plasma membrane residence of hyaluronan synthase is coupled to its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Osteopontin induction of hyaluronan synthase 2 expression promotes breast cancer malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

The over-expression of HAS2, Hyal-2 and CD44 is implicated in the invasiveness of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Antisense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronidases: their genomics, structures, and mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Degradative action of reactive oxygen species on hyaluronan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

A novel PKC-regulated mechanism controls CD44 ezrin association and directional cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

CD44 isoform-cytoskeleton interaction in oncogenic signaling and tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

The ankyrin-binding domain of CD44s is involved in regulating hyaluronic acid-mediated functions and prostate tumor cell transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Interaction between CD44 and the repeat domain of ankyrin promotes hyaluronic acid-mediated ovarian tumor cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

The hyaluronan receptor, CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

CD44-mediated oncogenic signaling and cytoskeleton activation during mammary tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Rho GTPases are over-expressed in human tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

The cell adhesion molecule, GP116, is a new CD44 variant (ex14/v10) involved in hyaluronic acid binding and endothelial cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610054200

21 January 2018

Identifiers

DOI

10.1074/JBC.M610054200

1 reference

17 September 2017

1 reference