Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans (Q40141881)

17 September 2017

title

Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans (English)

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17 September 2017

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Nakagomi-Hagihara R

1

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17 September 2017

Nakai D

series ordinal

2

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17 September 2017

Tokui T

series ordinal

3

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17 September 2017

language of work or name

English

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publication date

1 April 2007

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17 September 2017

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17 September 2017

volume

37

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17 September 2017

issue

4

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17 September 2017

page(s)

416-426

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Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients

17 September 2017

cites work

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https://api.crossref.org/works/10.1080%2F00498250601188808

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Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta

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Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules

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Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions

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Clinical pharmacokinetics of pravastatin: mechanisms of pharmacokinetic events

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Cisplatin-induced toxicity in immortalized renal cell lines established from transgenic mice harboring temperature sensitive SV40 large T-antigen gene

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Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.

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Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance

21 January 2018

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Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/

21 January 2018

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Simultaneous determination of gemfibrozil and its metabolites in plasma and urine by a fully automated high performance liquid chromatographic system

21 January 2018

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Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

21 January 2018

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Glucuronidation converts gemfibrozil to a potent, metabolism-dependent inhibitor of CYP2C8: implications for drug-drug interactions

21 January 2018

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Mechanistic studies on metabolic interactions between gemfibrozil and statins

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Severe rhabdomyolysis and cerivastatin-gemfibrozil combination therapy

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Molecular physiology of renal organic anion transporters

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Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions

21 January 2018

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Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A.

21 January 2018

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Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

21 January 2018

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Evaluation of drug-drug interaction in the hepatobiliary and renal transport of drugs

21 January 2018

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Isolation of a family of organic anion transporters from human liver and kidney

21 January 2018

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Molecular cloning and functional analyses of OAT1 and OAT3 from cynomolgus monkey kidney

21 January 2018

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Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid

21 January 2018

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Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors

21 January 2018

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Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter

21 January 2018

1 reference

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10.1080/00498250601188808

21 January 2018

Identifiers

DOI

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17 September 2017

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