Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis (Q40147027)

17 September 2017

title

Role of BRAF-V600E in the serrated pathway of colorectal tumourigenesis (English)

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17 September 2017

P Minoo

1

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17 September 2017

M P Moyer

series ordinal

2

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17 September 2017

J R Jass

series ordinal

3

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17 September 2017

publication date

1 June 2007

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17 September 2017

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17 September 2017

volume

212

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17 September 2017

issue

2

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17 September 2017

page(s)

124-133

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Epidemiology and prevention of colorectal cancer

17 September 2017

cites work

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21 January 2018

Cancer statistics, 2006

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Trends in the leading causes of death in the United States, 1970-2002.

21 January 2018

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Genetic alterations during colorectal-tumor development

21 January 2018

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

21 January 2018

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Microsatellite instability in cancer of the proximal colon

21 January 2018

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Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer

21 January 2018

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Morphology of sporadic colorectal cancer with DNA replication errors

21 January 2018

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Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas.

21 January 2018

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BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum

21 January 2018

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Promoter hypermethylation frequency and BRAF mutations distinguish hereditary non-polyposis colon cancer from sporadic MSI-H colon cancer.

21 January 2018

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BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer

21 January 2018

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Morphologic reappraisal of serrated colorectal polyps.

21 January 2018

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Serrated adenoma of the colorectum and the DNA-methylator phenotype

21 January 2018

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CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability.

21 January 2018

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Frequent CpG island methylation in serrated adenomas of the colorectum

21 January 2018

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Progressive methylation during the serrated neoplasia pathway of the colorectum.

21 January 2018

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NCM460, a normal human colon mucosal epithelial cell line

21 January 2018

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Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis.

21 January 2018

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MethyLight: a high-throughput assay to measure DNA methylation

21 January 2018

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Sensitive Detection of DNA Methylation

21 January 2018

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Precision and performance characteristics of bisulfite conversion and real-time PCR (MethyLight) for quantitative DNA methylation analysis

21 January 2018

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

21 January 2018

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Apoptosis index and apoptosis-related antigen expression in serrated adenoma of the colorectum: the saw-toothed structure may be related to inhibition of apoptosis

21 January 2018

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Apoptosis, anoikis and their relevance to the pathobiology of colon cancer

21 January 2018

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Epithelial-mesenchymal transitions in tumour progression

21 January 2018

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Mutations of the BRAF gene in human cancer

21 January 2018

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Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature

21 January 2018

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Emerging concepts in colorectal neoplasia

21 January 2018

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B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

21 January 2018

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BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms

21 January 2018

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The power and the promise of oncogene-induced senescence markers.

21 January 2018

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

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Senescence and serration: a new twist to an old tale

21 January 2018

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High frequency of BRAF mutations in nevi

21 January 2018

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BRAF mutation: a frequent event in benign, atypical, and malignant melanocytic lesions of the skin

21 January 2018

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Mutations of the BRAF gene in benign and malignant melanocytic lesions

21 January 2018

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Human melanocyte senescence and melanoma susceptibility genes

21 January 2018

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The INK4a/ARF locus and melanoma

21 January 2018

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

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Serrated adenomatous polyposis in humans.

21 January 2018

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

21 January 2018

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A core promoter and a frequent single-nucleotide polymorphism of the mismatch repair gene hMLH1.

21 January 2018

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Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells

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Regulation of DNA methylation by the Ras signaling pathway

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Epidemiology of colorectal cancer

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RAF/RAS oncogenes and mismatch-repair status

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21 January 2018

Identifiers

DOI

10.1002/PATH.2160

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17 September 2017

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