BGRT: biologically guided radiation therapy-the future is fast approaching! (Q40156602)

18 September 2017

BGRT: biologically guided radiation therapy-the future is fast approaching! (English)

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Adaptive radiation therapy

18 September 2017

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author name string

Robert D Stewart

series ordinal

1

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PubMed ID

17985619

18 September 2017

X Allen Li

series ordinal

2

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PubMed ID

17985619

18 September 2017

language of work or name

English

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publication date

1 October 2007

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18 September 2017

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18 September 2017

34

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10

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18 September 2017

3739-3751

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The modelled benefits of individualizing radiotherapy patients' dose using cellular radiosensitivity assays with inherent variability

18 September 2017

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A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy

21 January 2018

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Biological response to radiation therapy

21 January 2018

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Biologically optimized radiation therapy

21 January 2018

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Biologically optimized 3-dimensional in vivo predictive assay-based radiation therapy using positron emission tomography-computerized tomography imaging

21 January 2018

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Radiation therapy: intensity modulated, image guided, biologically optimized and evidence based.

21 January 2018

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[18F]fluoro-deoxy-glucose positron emission tomography ([18F]FDG-PET) voxel intensity-based intensity-modulated radiation therapy (IMRT) for head and neck cancer.

21 January 2018

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Survival prediction in high-grade gliomas by MRI perfusion before and during early stage of RT [corrected].

21 January 2018

1 reference

On biologically conformal boost dose optimization

21 January 2018

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Over the next decade the success of radiation treatment planning will be judged by the immediate biological response of tumor cells rather than by surrogate measures such as dose maximization and uniformity

21 January 2018

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Reporting and analyzing dose distributions: a concept of equivalent uniform dose

21 January 2018

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Organizational response of normal tissues to irradiation

21 January 2018

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Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology

21 January 2018

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Mechanisms of therapy-related carcinogenesis

21 January 2018

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A molecular theory of cell survival.

21 January 2018

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The link between low-LET dose-response relations and the underlying kinetics of damage production/repair/misrepair

21 January 2018

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Clinically relevant optimization of 3-D conformal treatments

21 January 2018

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Dose escalation in permanent brachytherapy for prostate cancer: dosimetric and biological considerations

21 January 2018

1 reference

Stereotactic body radiation therapy of lung tumors: preliminary experience using normal tissue complication probability-based dose limits

21 January 2018

1 reference

Modeling radiation pneumonitis risk with clinical, dosimetric, and spatial parameters

21 January 2018

1 reference

A model for calculating tumour control probability in radiotherapy including the effects of inhomogeneous distributions of dose and clonogenic cell density.

21 January 2018

1 reference

Fitting tumor control probability models to biopsy outcome after three-dimensional conformal radiation therapy of prostate cancer: pitfalls in deducing radiobiologic parameters for tumors from clinical data

21 January 2018

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21 January 2018

Modeling tumor growth

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Investigation of various growth mechanisms of solid tumour growth within the linear-quadratic model for radiotherapy.

21 January 2018

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Radiation-induced chromosome aberrations: insights gained from biophysical modeling

21 January 2018

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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

21 January 2018

1 reference

Sensing and repairing DNA double-strand breaks

21 January 2018

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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

21 January 2018

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A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation.

21 January 2018

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Monte carlo simulation of base and nucleotide excision repair of clustered DNA damage sites. II. Comparisons of model predictions to measured data

21 January 2018

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Mutagenic effects of a single and an exact number of alpha particles in mammalian cells

21 January 2018

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Studies of bystander effects in human fibroblasts using a charged particle microbeam

21 January 2018

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Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells

21 January 2018

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Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect

21 January 2018

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Radiation-induced bystander effects: past history and future directions

21 January 2018

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21 January 2018

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Impact of prolonged fraction delivery times on tumor control: a note of caution for intensity-modulated radiation therapy (IMRT).

21 January 2018

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A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

21 January 2018

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Low-dose hyper-radiosensitivity: a consequence of ineffective cell cycle arrest of radiation-damaged G2-phase cells.

21 January 2018

1 reference

Induced radioresistance: an overview and historical perspective

21 January 2018

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Adaptive response and induced resistance.

21 January 2018

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21 January 2018

Pharmacokinetic modeling

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Effect of heterogeneity in radiosensitivity on LQ based isoeffect formalism for low α/β cancers

21 January 2018

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Incorporating model parameter uncertainty into inverse treatment planning.

21 January 2018

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Is alpha/beta for prostate tumors really low?

21 January 2018

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Tumour hypoxia and vascular density as predictors of metastasis in squamous cell carcinoma of the uterine cervix

21 January 2018

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Hypoxia dose painting by numbers: a planning study.

21 January 2018

1 reference

Theragnostic imaging for radiation oncology: dose-painting by numbers

21 January 2018

1 reference

Effects of oxygen on intrinsic radiation sensitivity: A test of the relationship between aerobic and hypoxic linear-quadratic (LQ) model parameters

21 January 2018

1 reference

Dose escalation to combat hypoxia in prostate cancer: a radiobiological study on clinical data

21 January 2018

1 reference

Analysis of a large number of clinical studies for breast cancer radiotherapy: estimation of radiobiological parameters for treatment planning

21 January 2018

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An estimation of radiobiologic parameters from clinical outcomes for radiation treatment planning of brain tumor.

21 January 2018

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Prediction of sensitivity of rectal cancer cells in response to preoperative radiotherapy by DNA microarray analysis of gene expression profiles.

21 January 2018

1 reference

Current imaging paradigms in radiation oncology

21 January 2018

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The role of positron emission tomography in radiation treatment planning

21 January 2018

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Positron emission tomography for prostate, bladder, and renal cancer

21 January 2018

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The role of diffusion tensor imaging in establishing the proximity of tumor borders to functional brain systems: implications for preoperative risk assessments and postoperative outcomes

21 January 2018

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Hypoxia imaging in brain tumors

21 January 2018

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MRI of the tumor microenvironment.

21 January 2018

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Combined magnetic resonance imaging and spectroscopic imaging approach to molecular imaging of prostate cancer

21 January 2018

1 reference

In vivo molecular imaging for planning radiation therapy of gliomas: an application of 1H MRSI.

21 January 2018

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Biomedical Imaging Research Opportunities Workshop II: a summary of findings and recommendations

21 January 2018

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Development of an inverse optimization package to plan nonuniform dose distributions based on spatially inhomogeneous radiosensitivity extracted from biological images.

21 January 2018

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Use of principal component analysis to evaluate the partial organ tolerance of normal tissues to radiation

21 January 2018

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Does Variation in thein VitroCellular Radiosensitivity Explain the Shallow Clinical Dose—control Curve for Malignant Melanoma?

21 January 2018

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Steepness of the Clinical Dose–control Curve and Variation in thein VitroRadiosensitivity of Head and Neck Squamous Cell Carcinoma

21 January 2018

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Dose-Survival Curves of Human Cells in Tissue Culture Irradiated with Alpha-, Beta-, 20-KV. X- and 200-KV. X-Radiation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1118/1.2779861

1 reference

18 September 2017

1 reference

PubMed ID

17985619