Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir. (Q40157684)

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27 December 2019

title

Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir (English)

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27 December 2019

7

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author name string

Jacqueline C Ruiz

1

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27 December 2019

James R Beadle

2

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27 December 2019

Kathy A Aldern

3

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Kathy A Keith

4

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Caroll B Hartline

5

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Earl R Kern

6

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publication date

10 October 2006

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27 December 2019

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volume

75

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issue

1

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27 December 2019

page(s)

87-90

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Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro

27 December 2019

cites work

1 reference

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Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir

22 September 2017

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Inhibitory activity of alkoxyalkyl and alkyl esters of cidofovir and cyclic cidofovir against orthopoxvirus replication in vitro

22 September 2017

1 reference

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Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir.

22 September 2017

1 reference

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Phosphonomethoxyalkyl Analogs of Nucleotides

22 September 2017

1 reference

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Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro

22 September 2017

1 reference

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Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir

22 September 2017

1 reference

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Alkylglycerol prodrugs of phosphonoformate are potent in vitro inhibitors of nucleoside-resistant human immunodeficiency virus type 1 and select for resistance mutations that suppress zidovudine resistance

22 September 2017

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Clinical pharmacokinetics of the antiviral nucleotide analogues cidofovir and adefovir

22 September 2017

1 reference

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Lipid prodrugs of phosphonoacids: greatly enhanced antiviral activity of 1-O-octadecyl-sn-glycero-3-phosphonoformate in HIV-1, HSV-1 and HCMV-infected cells, in vitro

22 September 2017

1 reference

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Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine

25 September 2017

1 reference

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Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection.

17 June 2018

1 reference

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Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model

20 August 2018

1 reference

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Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-(14)C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism.

20 August 2018

1 reference

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Mechanism of uptake of the phosphonate analog (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in Vero cells

20 August 2018

1 reference

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10.1016/J.ANTIVIRAL.2006.09.005

20 August 2018

Identifiers

DOI

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27 December 2019

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27 December 2019

PubMed publication ID

17367874

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