The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashion (Q40157700)

18 September 2017

The adenovirus E4orf6 E3 ubiquitin ligase complex assembles in a novel fashion (English)

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18 September 2017

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Chi Ying Cheng

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18 September 2017

Paola Blanchette

series ordinal

2

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18 September 2017

Philip E Branton

series ordinal

3

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18 September 2017

language of work or name

English

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publication date

23 March 2007

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18 September 2017

9

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based on heuristic

inferred from page(s)

published in

Virology

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18 September 2017

364

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18 September 2017

36-44

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18 September 2017

1

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Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

18 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Genetic analysis of a potential zinc-binding domain of the adenovirus E4 34k protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

The SCF ubiquitin ligase: insights into a molecular machine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

The Mre11 complex is required for ATM activation and the G2/M checkpoint

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

A functional complex of adenovirus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Inhibition of transcription elongation by the VHL tumor suppressor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

The SCF ubiquitin ligase: an extended look

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

A zinc-binding region in Vif binds Cul5 and determines cullin selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

The adenovirus E4orf6 protein can promote E1A/E1B-induced focus formation by interfering with p53 tumor suppressor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Zinc chelation inhibits HIV Vif activity and liberates antiviral function of the cytidine deaminase APOBEC3G.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.02.012

10.1016/J.VIROL.2007.02.012

7 January 2021

Identifiers

DOI

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18 September 2017

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