The mechanism of action of quinone antibiotics (Q40158566)

18 September 2017

1 reference

title

The mechanism of action of quinone antibiotics (English)

1 reference

18 September 2017

1 reference

5 October 2023

author name string

J. W. Lown

series ordinal

1

1 reference

PubMed ID

6353197

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6353197

5 October 2023

language of work or name

1 reference

1 January 1983

1 reference

PubMed ID

6353197

full work available at URL

18 September 2017

http://link.springer.com/content/pdf/10.1007/BF00229240.pdf

file format

Portable Document Format

1 reference

http://link.springer.com/article/10.1007/BF00229240/fulltext.html

5 October 2023

1 reference

http://link.springer.com/content/pdf/10.1007/BF00229240

5 October 2023

1 reference

Molecular and Cellular Biochemistry

5 October 2023

published in

1 reference

18 September 2017

55

1 reference

18 September 2017

1

1 reference

18 September 2017

17-40

1 reference

https://scigraph.springernature.com/pub.10.1007/bf00229240

18 September 2017

0 references

cites work

Hydroxyl radical production by free and DNA-bound aminoquinone antibiotics and its role in DNA degradation. Electron spin resonance detection of hydroxyl radicals by spin trapping

1 reference

12 December 2020

THE ACTION OF STREPTONIGRIN ON BACTERIAL DNA METABOLISM AND ON INDUCTION OF PHAGE PRODUCTION IN LYSOGENIC BACTERIA

1 reference

12 December 2020

Molecular structure of an anticancer drug-DNA complex: daunomycin plus d(CpGpTpApCpG).

1 reference

12 December 2020

Binding of streptonigrin to DNA

1 reference

12 December 2020

Adriamycin (NSC-123,127): a new antibiotic with antitumor activity

1 reference

12 December 2020

Generation of free radicals of quinone group-containing anti-cancer chemicals in NADPH-microsome system as evidenced by initiation of sulfite oxidation

1 reference

12 December 2020

A proposed reaction mechanism for the enzymatic reductive cleavage of glycosidic bond in anthracycline antibiotics

1 reference

12 December 2020

Generation of free radicals from phenazine methosulfate, streptonigrin, and riboflavin in bacterial suspensions

1 reference

12 December 2020

Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Comparative aspects of anthramycin, tomaymycin and sibiromycin

1 reference

12 December 2020

THE EFFECT OF GLUCOSE PRETREATMENT ON THE CARCINOSTATIC AND TOXIC ACTIVITIES OF SOME ALKYLATING AGENTS

1 reference

12 December 2020

Interference of daunomycin with metabolic events of the cell cycle in synchronized cultures of rat fibroblasts

1 reference

12 December 2020

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

1 reference

12 December 2020

Inhibition of DNA and RNA metabolism by daunorubicin and adriamycin in L1210 mouse leukemia

1 reference

12 December 2020

Binding of daunomycin to DNA and the inhibition of RNA and DNA synthesis

1 reference

12 December 2020

Streptonigrin-transition metal complexes: Binding to DNA and biological activity

1 reference

12 December 2020

Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects

1 reference

12 December 2020

Electron spin resonance study on the mode of generation of free radicals of daunomycin, adriamycin, and carboquone in NAD(P)H-microsome system

1 reference

12 December 2020

Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation

1 reference

12 December 2020

Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin

1 reference

12 December 2020

ACTIVITY OF DAUNOMYCIN, A NEW ANTITUMOR ANTIBIOTIC, ON NORMAL AND NEOPLASTIC CELLS GROWN IN VITRO

1 reference

12 December 2020

Streptonigrin, an antitumor substance. I. Isolation and characterization

1 reference

12 December 2020

Quinone natural products: streptonigrin (NSC-45383) and lapachol (NSC-11905) structure-activity relationships

1 reference

12 December 2020

Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity

1 reference

12 December 2020

Adriamycin stimulated superoxide formation in submitochondrial particles

1 reference

12 December 2020

Binding of saframycin A, a heterocyclic quinone anti-tumor antibiotic to DNA as revealed by the use of the antibiotic labeled with [14C]tyrosine or [14C]cyanide

1 reference

12 December 2020

Lethal action and metabolic effects of streptonigrin on Escherichia coli

1 reference

12 December 2020

Role of one-electron and two-electron reduction products of adriamycin and daunomycin in deoxyribonucleic acid binding

1 reference

12 December 2020

Bohemic acid complex. Biological characterization of the antibiotics, musettamycin and marcellomycin

1 reference

12 December 2020

Differential Fluorescent Staining of Human Chromosomes with Daunomycin and Adriamycin—The D-Bands

1 reference

12 December 2020

1 reference

12 December 2020

Enzymatic defenses against the toxicity of oxygen and of streptonigrin in Escherichia coli

1 reference

12 December 2020

The mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro

1 reference

12 December 2020

Irreversible binding of reductively activated streptonigrin to nucleic acids in the presence of metals

1 reference

12 December 2020

D-glucosamine and L-citrulline, precursors in mitomycin biosynthesis by Streptomyces verticillatus

1 reference

12 December 2020

The structure of a novel antitumor antibiotic, saframycin A

1 reference

12 December 2020

New antibiotics saframycins A, B, C, D and E.

1 reference

12 December 2020

Adriamycin: a proposal on the specificity of drug action

1 reference

12 December 2020

New mitomycin, 10-decarbamoyloxy-9-dehydromitomycin B from Streptomyces caespitosus

1 reference

12 December 2020

Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids

1 reference

12 December 2020

Effects of streptonigrin on nucleic acid metabolism of tissue culture cells

1 reference

12 December 2020

Rat liver daunorubicin reductase. An aldo-keto reductase

1 reference

12 December 2020

Mitomycin derivatives. 1. Preparation of mitosane and mitosene compounds and their biological activities

1 reference

12 December 2020

Increased production of saframycin A and isolation of saframycin S

1 reference

12 December 2020

A quantitative spectrophotometric method to measure plant lectin-induced cell agglutination.

1 reference

12 December 2020

The crystal and molecular structure of N-brosylmitomycin A

1 reference

12 December 2020

Adriamycin and Daunorubicin Inhibition of Mutant T4 DNA Polymerases

1 reference

12 December 2020

Review: ethidium fluorescence assays. Part 1. Physicochemical studies

1 reference

12 December 2020

Mitomycin, a new antibiotic from Streptomyces. I.

1 reference

12 December 2020

Mode of action of saframycin A, a novel heterocyclic quinone antibiotic. Inhibition of RNA synthesis in vivo and in vitro

1 reference

12 December 2020

A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS

1 reference

12 December 2020

H2O2 generation during the redox cycle of mitomycin C and dna-bound mitomycin C.

1 reference

12 December 2020

Action of mitomycin C on nucleic acid metabolism in tumor and bacterial cells

1 reference

12 December 2020

Bioactivation as a model for drug design bioreductive alkylation

1 reference

12 December 2020

The mechanism of the degradation of DNA by streptonigrin

1 reference

12 December 2020

Molecular and crystal structure of streptonigrin

1 reference

12 December 2020

Effect of mitomycin C on the synthesis of bacterial and viral deoxyribonucleic acid

1 reference

12 December 2020

Molecular mechanisms of binding and single-strand scission of deoxyribonucleic acid by the antitumor antibiotics saframycins A and C

1 reference

12 December 2020

N-trifluoroacetyladriamycin-14-valerate, an analog with greater experimental antitumor activity and less toxicity than adriamycin

1 reference

12 December 2020

Novel assay of 7-alkylation of guanine residues in DNA. Application to nitrogen mustard, triethylenemelamine and mitomycin C

1 reference

12 December 2020

A fluorescent complex between ethidium bromide and nucleic acids. Physical-chemical characterization

1 reference

12 December 2020

Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents

1 reference

12 December 2020

[Study of bruneomycin formed by Act. albus var. bruneomycini and its identification with streptonigrin].

1 reference

12 December 2020

Microbial conversion of saframycin A to 25-dihydrosaframycin A and 21-decyano-25-dihydrosaframycin A (25-dihydrosaframycin B) and their biological activities

1 reference

12 December 2020

Increased sensitivity of the Walker tumour towards aromatic nitrogen mustards carrying basic side chains following glucose pretreatment

1 reference

12 December 2020

New antibiotics, saframycins A, B, C, D and E.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.30.1015

Identifiers

DOI

10.1007/BF00229240

1 reference

18 September 2017

1 reference

PubMed ID

6353197