Phosphoinositide 3-kinase is required for high glucose-induced hypertrophy and p21WAF1 expression in LLC-PK1 cells (Q40164351)

18 September 2017

Phosphoinositide 3-kinase is required for high glucose-induced hypertrophy and p21WAF1 expression in LLC-PK1 cells (English)

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18 September 2017

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T-D Chuang

1

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18 September 2017

J-Y Guh

2

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18 September 2017

S-J Chiou

3

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18 September 2017

H-C Chen

4

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18 September 2017

J-S Huang

5

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18 September 2017

Y-L Yang

6

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18 September 2017

L-Y Chuang

7

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18 September 2017

language of work or name

English

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publication date

28 February 2007

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18 September 2017

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18 September 2017

71

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18 September 2017

9

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18 September 2017

867-874

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https://scigraph.springernature.com/pub.10.1038/sj.ki.5002155

18 September 2017

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cites work

From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines

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7 January 2021

Tubular changes in early diabetic nephropathy.

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7 January 2021

The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy

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7 January 2021

Cell cycle inhibitors (p27Kip1 and p21CIP1) cause hypertrophy in LLC-PK1 cells

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7 January 2021

Unravelling the activation mechanisms of protein kinase B/Akt

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7 January 2021

Phosphoinositide 3-kinase controls early and late events in mammalian cell division

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7 January 2021

Activation of renal signaling pathways in db/db mice with type 2 diabetes

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7 January 2021

Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy

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7 January 2021

ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells

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7 January 2021

G1 kinases and transforming growth factor-beta signaling are associated with a growth pattern switch in diabetes-induced renal growth

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7 January 2021

High glucose inhibits renal proximal tubule cell proliferation and involves PKC, oxidative stress, and TGF-beta 1.

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7 January 2021

The role of cell cycle proteins in Glomerular disease

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New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

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7 January 2021

Lost in transcription: p21 repression, mechanisms, and consequences

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7 January 2021

Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1).

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7 January 2021

Increased glomerular and tubular expression of transforming growth factor-beta1, its type II receptor, and activation of the Smad signaling pathway in the db/db mouse

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7 January 2021

Role of TGF-beta signaling in extracellular matrix production under high glucose conditions.

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7 January 2021

Both Sp1 and Smad participate in mediating TGF-beta1-induced HGF receptor expression in renal epithelial cells

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7 January 2021

Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway

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7 January 2021

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

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7 January 2021

Osteopontin: correlation with interstitial fibrosis in human diabetic kidney and PI3-kinase-mediated enhancement of expression by glucose in human proximal tubular epithelial cells

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7 January 2021

Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells

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7 January 2021

The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypert

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7 January 2021

Vascular endothelial growth factor induces protein synthesis in renal epithelial cells: a potential role in diabetic nephropathy

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7 January 2021

Oncogenic PI3K deregulates transcription and translation

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7 January 2021

Expression of p21(WAF1/Cip1) through Sp1 sites by histone deacetylase inhibitor apicidin requires PI 3-kinase-PKC epsilon signaling pathway

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7 January 2021

Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation

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7 January 2021

Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

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7 January 2021

The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1

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7 January 2021

Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.

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7 January 2021

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

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7 January 2021

TGF beta signals through a heteromeric protein kinase receptor complex

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7 January 2021

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

1 reference

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7 January 2021

Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3.

1 reference

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7 January 2021

Adhesion-independent alpha6beta4 integrin clustering is mediated by phosphatidylinositol 3-kinase

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7 January 2021

Effect of nitric oxide-cGMP-dependent protein kinase activation on advanced glycation end-product-induced proliferation in renal fibroblasts

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.KI.5002155

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Dimensions Publication ID

18 September 2017

1021974842

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Fatcat ID

release_sa3co2oevbd7vnkrdiluf7pyca

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Fatcat

https://api.fatcat.wiki/v0/release/sa3co2oevbd7vnkrdiluf7pyca

24 November 2022

mapped directly with Wikidata item

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