Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits (Q40166036)

18 September 2017

Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits (English)

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18 September 2017

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Francesca Zimetti

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author name string

Lee A Morehouse

1

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18 September 2017

Eliot D Sugarman

2

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18 September 2017

Patricia-Ann Bourassa

3

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18 September 2017

Thomas M Sand

4

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18 September 2017

Feng Gao

6

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18 September 2017

George H Rothblat

7

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18 September 2017

Anthony J Milici

8

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18 September 2017

26 February 2007

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Journal of Lipid Research

18 September 2017

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18 September 2017

48

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18 September 2017

6

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18 September 2017

1263-1272

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High-density lipoprotein cholesterol as an independent risk factor in cardiovascular disease: assessing the data from Framingham to the Veterans Affairs High--Density Lipoprotein Intervention Trial

18 September 2017

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Antiinflammatory properties of HDL.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

The oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDL.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

High-density lipoprotein enhancement of anticoagulant activities of plasma protein S and activated protein C.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Evidence that high-density lipoprotein cholesterol is an independent predictor of acute platelet-dependent thrombus formation.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

A review of CETP and its relation to atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Cholesteryl ester transfer protein expression attenuates atherosclerosis in ovariectomized mice

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Delayed catabolism of high density lipoprotein apolipoproteins A-I and A-II in human cholesteryl ester transfer protein deficiency

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Plasma lipid transfer protein as a determinant of the atherogenicity of monkey plasma lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Monoclonal antibody inhibition of cholesteryl ester transfer protein activity in the rabbit. Effects on lipoprotein composition and high density lipoprotein cholesteryl ester metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Is there a need for cholesteryl ester transfer protein inhibition?

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Measurement of cholesterol bidirectional flux between cells and lipoproteins

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

In vivo modulation of HDL phospholipid has opposing effects on SR-BI- and ABCA1-mediated cholesterol efflux

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Description of the torcetrapib series of cholesteryl ester transfer protein inhibitors, including mechanism of action

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Postprandial myocardial perfusion in healthy subjects and in type 2 diabetic patients.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Effect of HDL, from Japanese white rabbit administered a new cholesteryl ester transfer protein inhibitor JTT-705, on cholesteryl ester accumulation induced by acetylated low density lipoprotein in J774 macrophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: in vivo studies in rabbits.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

New insights into the regulation of HDL metabolism and reverse cholesterol transport

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Stimulation of fecal steroid excretion after infusion of recombinant proapolipoprotein A-I. Potential reverse cholesterol transport in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600332-JLR200

10.1194/JLR.M600332-JLR200

21 January 2018

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DOI

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18 September 2017

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