A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome (Q40174315)

18 September 2017

A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome (English)

1 reference

18 September 2017

Yong Pan

1

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18 September 2017

Baolin Wang

series ordinal

2

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18 September 2017

language of work or name

English

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publication date

5 February 2007

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Journal of Biological Chemistry

18 September 2017

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18 September 2017

282

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18 September 2017

15

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18 September 2017

10846-10852

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Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Enzymes catalyzing ubiquitination and proteolytic processing of the p105 precursor of nuclear factor kappaB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

The generation of nfkb2 p52: mechanism and efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

A glycine-rich region in NF-kappaB p105 functions as a processing signal for the generation of the p50 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Processing of the Drosophila hedgehog signaling effector Ci-155 to the repressor Ci-75 is mediated by direct binding to the SCF component Slimb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

A hypermorphic mouse Gli3 allele results in a polydactylous limb phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Dual degradation signals control Gli protein stability and tumor formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

Endoproteolytic activity of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

The acceleration of cosmic-ray protons in the supernova remnant RX J1713.7–3946

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608599200

21 January 2018

Identifiers

DOI

10.1074/JBC.M608599200

1 reference

release_4ifqljtm5babljwaxqa7z2r5py

18 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4ifqljtm5babljwaxqa7z2r5py

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference