Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-delta. (Q40203788)

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scientific article published on 27 November 2006

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English	Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-delta.	scientific article published on 27 November 2006

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22 December 2019

Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-delta (English)

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22 December 2019

Masahide Yamamoto

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22 December 2019

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Kurosu T

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22 December 2019

Tsuji K

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22 December 2019

Kida A

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22 December 2019

Koyama T

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22 December 2019

Miura O

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27 November 2006

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22 December 2019

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22 December 2019

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22 December 2019

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22 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210117

0 references

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Rottlerin, a novel protein kinase inhibitor

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