The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors (Q40220162)

18 September 2017

The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors (English)

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18 September 2017

Andreas Breit

1

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18 September 2017

Katharina Wolff

2

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18 September 2017

Hermann Kalwa

3

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18 September 2017

Hubertus Jarry

4

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18 September 2017

Thomas Büch

5

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18 September 2017

Thomas Gudermann

6

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18 September 2017

language of work or name

English

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publication date

14 October 2006

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Journal of Biological Chemistry

18 September 2017

10

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based on heuristic

inferred from page(s)

published in

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18 September 2017

281

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18 September 2017

49

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18 September 2017

37447-37456

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Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway

18 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Role of endocytosis in signalling and regulation of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Cloning of the mouse agouti gene predicts a secreted protein ubiquitously expressed in mice carrying the lethal yellow mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Molecular characterization of the mouse agouti locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Overexpression of Agrt leads to obesity in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Inverse agonist activity of agouti and agouti-related protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Down-regulation of melanocortin receptor signaling mediated by the amino terminus of Agouti protein in Xenopus melanophores

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Agonist-Dependent Internalization of the Human Melanocortin-4 Receptors in Human Embryonic Kidney 293 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Characterization of cell lines stably expressing human normal or mutated EGFP-tagged MC4R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Real-time monitoring of ubiquitination in living cells by BRET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Subcellular distribution of GABA(B) receptor homo- and hetero-dimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Hetero-oligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Palmitoylation of the V2 vasopressin receptor carboxyl tail enhances beta-arrestin recruitment leading to efficient receptor endocytosis and ERK1/2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Expression of functional melanocortin-4 receptor in the hypothalamic GT1-1 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

G-protein-coupled receptor heterodimerization modulates receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Agonist activated adrenocorticotropin receptor internalizes via a clathrin-mediated G protein receptor kinase dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Agonist-induced endocytosis and recycling of the gonadotropin-releasing hormone receptor: effect of beta-arrestin on internalization kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Palmitoylation of the 5-hydroxytryptamine4a receptor regulates receptor phosphorylation, desensitization, and beta-arrestin-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

Melanocortin receptor signaling through mitogen-activated protein kinase in vitro and in rat hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

The melanocortin system and energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605982200

21 January 2018

Identifiers

DOI

10.1074/JBC.M605982200

1 reference

18 September 2017

1 reference