TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains. (Q40230123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984230%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains (English)

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30 December 2019

1

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30 December 2019

author name string

Edward S Dornan

series ordinal

2

1 reference

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30 December 2019

Mary M Donaldson

series ordinal

3

1 reference

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30 December 2019

Iain M Morgan

series ordinal

4

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30 December 2019

language of work or name

English

0 references

publication date

1 December 2006

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30 December 2019

number of pages

10

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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30 December 2019

volume

400

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30 December 2019

issue

3

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30 December 2019

page(s)

573-582

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984230%20AND%20SRC:MED&resulttype=core&format=json

Aberrant expression of TopBP1 in breast cancer.

30 December 2019

cites work

1 reference

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TopBP1 activates the ATR-ATRIP complex

22 September 2017

1 reference

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The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair

22 September 2017

1 reference

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Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

22 September 2017

1 reference

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Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Human TopBP1 ensures genome integrity during normal S phase

22 September 2017

1 reference

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Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage

22 September 2017

1 reference

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Identification of TopBP1 as a c-Abl-interacting protein and a repressor for c-Abl expression

22 September 2017

1 reference

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Identification and functional analysis of TopBP1 and its homologs

22 September 2017

1 reference

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Viral transport of DNA damage that mimics a stalled replication fork

22 September 2017

1 reference

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Interactions between BRCT repeats and phosphoproteins: tangled up in two

22 September 2017

1 reference

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Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality

22 September 2017

1 reference

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Molecular functions of BRCA1 in the DNA damage response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Expression of MCM10 and TopBP1 is regulated by cell proliferation and UV irradiation via the E2F transcription factor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Both DNA topoisomerase II-binding protein 1 and BRCA1 regulate the G2-M cell cycle checkpoint

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

BRCA1 associates with human papillomavirus type 18 E2 and stimulates E2-dependent transcription

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Dynamic chromatin alterations triggered by natural and synthetic activation domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

The Xenopus Xmus101 protein is required for the recruitment of Cdc45 to origins of DNA replication

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Negative regulation of the mammalian UV response by Myc through association with Miz-1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

22 September 2017

1 reference

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Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

BRCT domain-containing protein TopBP1 functions in DNA replication and damage response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

A functional comparison of BRCA1 C-terminal domains in transcription activation and chromatin remodeling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

The BRCA1 C-terminal domain: structure and function.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Functional assay for BRCA1: mutagenesis of the COOH-terminal region reveals critical residues for transcription activation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Conserved BRCT regions of TopBP1 and of the tumor suppressor BRCA1 bind strand breaks and termini of DNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Coupling of DNA replication and mitosis by fission yeast rad4/cut5.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Regulation of the Wilms' tumour suppressor protein transcriptional activation domain.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

UVB irradiation reduces the half-life and transactivation potential of the human papillomavirus 16 E2 protein

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Novel cellular interacting partners of the human papillomavirus 16 transcription/replication factor E2.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698607

Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16984230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20060831

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984230%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984230%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

16984230

1 reference