Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities. (Q40232259)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Novel agonist monoclonal antibodies activate TrkB receptors and demonstrate potent neurotrophic activities (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Ming D Qian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Jie Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Xiang-Yang Tan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Andrew Wood

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Davinder Gill

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Seongeun Cho

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

1 September 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

number of pages

10

1 reference

inferred from page(s)

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

9394-9403

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

Extracellular-regulated kinases and phosphatidylinositol 3-kinase are involved in brain-derived neurotrophic factor-mediated survival and neuritogenesis of the neuroblastoma cell line SH-SY5Y.

30 December 2019

cites work

1 reference

12 December 2020

Neurotrophin signaling via Trks and p75.

1 reference

12 December 2020

The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site

1 reference

12 December 2020

Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia.

1 reference

12 December 2020

A phase I/II trial of recombinant methionyl human brain derived neurotrophic factor administered by intrathecal infusion to patients with amyotrophic lateral sclerosis.

1 reference

12 December 2020

Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5

1 reference

12 December 2020

A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein

1 reference

12 December 2020

Mu-opioid receptor activation prevents apoptosis following serum withdrawal in differentiated SH-SY5Y cells and cortical neurons via phosphatidylinositol 3-kinase.

1 reference

12 December 2020

Nerve growth factor mediates signal transduction through trk homodimer receptors

1 reference

12 December 2020

Photochemical stroke and brain-derived neurotrophic factor (BDNF) mRNA expression

1 reference

12 December 2020

BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model.

1 reference

12 December 2020

Adenovirus vector-mediated in vivo gene transfer of brain-derived neurotrophic factor (BDNF) promotes rubrospinal axonal regeneration and functional recovery after complete transection of the adult rat spinal cord.

1 reference

12 December 2020

Neurotrophins protect against cytosine arabinoside-induced apoptosis of immature rat cerebellar neurons

1 reference

12 December 2020

Overcoming the inhibitors of myelin with a novel neurotrophin strategy

1 reference

12 December 2020

Autonomic dysfunction in ALS: a preliminary study on the effects of intrathecal BDNF.

1 reference

12 December 2020

Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid

1 reference

12 December 2020

Cyclic-AMP response element-based signaling assays for characterization of Trk family tyrosine kinases modulators

1 reference

12 December 2020

Expression of trk receptors in the developing and adult human central and peripheral nervous system

1 reference

12 December 2020

Structural determinants of neurotrophin action.

1 reference

12 December 2020

Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins

1 reference

12 December 2020

The p75 neurotrophin receptor

1 reference

12 December 2020

Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity

1 reference

12 December 2020

TrkA cross-linking mimics neuronal responses to nerve growth factor

1 reference

12 December 2020

Formation of heterodimers from three neurotrophins, nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor.

1 reference

12 December 2020

Identification of TrkB autophosphorylation sites and evidence that phospholipase C-gamma 1 is a substrate of the TrkB receptor

1 reference

12 December 2020

Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells

1 reference

12 December 2020

Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury.

1 reference

12 December 2020

Potent human p140-TrkA agonists derived from an anti-receptor monoclonal antibody.

1 reference

12 December 2020

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

1 reference

12 December 2020

Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

1 reference

12 December 2020

The role of neuronal growth factors in neurodegenerative disorders of the human brain

1 reference

12 December 2020

Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors

1 reference

12 December 2020

10.1523/JNEUROSCI.1118-06.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

release_bhb7o2k35jh3hoyeucxe5tww2e

30 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bhb7o2k35jh3hoyeucxe5tww2e

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16971523%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference