Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. (Q40234208)

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scientific article published on 8 September 2006

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English	Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.	scientific article published on 8 September 2006

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scholarly article

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30 December 2019

Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin (English)

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30 December 2019

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multiple drug resistance

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Pornngarm Limtrakul

1

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30 December 2019

Pornngarm Limtrakul

2

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30 December 2019

author name string

Wanida Chearwae

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30 December 2019

Suneet Shukla

4

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30 December 2019

Chada Phisalphong

5

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30 December 2019

Suresh V Ambudkar

6

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language of work or name

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publication date

8 September 2006

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30 December 2019

Molecular and Cellular Biochemistry

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296

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1-2

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85-95

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30 December 2019

https://scigraph.springernature.com/pub.10.1007/s11010-006-9302-8

0 references

Resistance modification by PSC-833, a novel non-immunosuppressive cyclosporin A

1 reference

https://api.crossref.org/works/10.1007%2FS11010-006-9302-8

21 January 2018

Recent studies on the biofunctions and biotransformations of curcumin

1 reference

https://api.crossref.org/works/10.1007%2FS11010-006-9302-8

21 January 2018

Inhibitory effects of curcumin and tetrahydrocurcuminoids on the tumor promoter-induced reactive oxygen species generation in leukocytes in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS11010-006-9302-8

21 January 2018

Inhibition of P-glycoprotein activity and reversal of multidrug resistance in vitro by rosemary extract.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

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Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance protein 4 (ABCC4)-mediated ATP hydrolysis: effect of transport substrates and characterization of the post-hydrolysis transition state

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

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Hydrogen-bonding and C-H...pi interactions in 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione (tetrahydrocurcumin).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

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Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

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Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

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Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

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Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the catalytic cycle of ATP hydrolysis by human P-glycoprotein. The two ATP hydrolysis events in a single catalytic cycle are kinetically similar but affect different functional outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the role of glycosylation in accessibility of the extracellular domains of human MRP1 (ABCC1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

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Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of action of multidrug-resistance-linked P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of P-glycoprotein expression on sensitivity to hormones in MCF-7 human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological activities of Curcuma longa L.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-stimulatable ATPase activity in crude membranes of human MDR1-transfected mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biotransformation of curcumin through reduction and glucuronidation in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABC-transporters: implications on drug resistance from microorganisms to human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABC Transporters: From Microorganisms to Man

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of cancer chemoprevention by curcumin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticancer potential of curcumin: preclinical and clinical studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance in cancer: role of ATP-dependent transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation by LY335979 of P-glycoprotein function in multidrug-resistant cell lines and human natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photoaffinity probes for the alpha 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased oral bioavailability of paclitaxel by GF120918 in mice through selective modulation of P-glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16960658

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-006-9302-8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16960658%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16960658%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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