Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation. (Q40234850)

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29 December 2019

title

Elevated activity of STAT3C due to higher DNA binding affinity of phosphotyrosine dimer rather than covalent dimer formation (English)

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2

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29 December 2019

author name string

Li Li

series ordinal

1

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language of work or name

English

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publication date

6 September 2006

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Journal of Biological Chemistry

29 December 2019

published in

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29 December 2019

volume

281

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issue

44

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page(s)

33172-33181

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The role of STATs in transcriptional control and their impact on cellular function

29 December 2019

cites work

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Three-dimensional structure of the Stat3beta homodimer bound to DNA

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STAT proteins and transcriptional responses to extracellular signals

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Cytoplasmic transport of Stat3 by receptor-mediated endocytosis

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Constitutive and IFN-gamma-induced nuclear import of STAT1 proceed through independent pathways

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DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.

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STATs dimerize in the absence of phosphorylation

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STAT3 forms stable homodimers in the presence of divalent cations prior to activation.

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Cytoplasmic STAT proteins associate prior to activation.

21 January 2018

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Preassociation of nonactivated STAT3 molecules demonstrated in living cells using bioluminescence resonance energy transfer: a new model of STAT activation?

21 January 2018

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Analysis of Stat3 (signal transducer and activator of transcription 3) dimerization by fluorescence resonance energy transfer in living cells

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Structural bases of unphosphorylated STAT1 association and receptor binding

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Structure of the unphosphorylated STAT5a dimer

21 January 2018

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

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Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

21 January 2018

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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

21 January 2018

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Stat3 activation by Src induces specific gene regulation and is required for cell transformation

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Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

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Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines

21 January 2018

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Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

21 January 2018

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A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

21 January 2018

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Cellular physiology of STAT3: Where's the cytoplasmic monomer?

21 January 2018

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A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.

21 January 2018

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Mutational analysis of acute-phase response factor/Stat3 activation and dimerization

21 January 2018

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A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.

21 January 2018

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A reinterpretation of the dimerization interface of the N-terminal domains of STATs

21 January 2018

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Structure and mechanism of the RNA polymerase II transcription machinery

21 January 2018

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Modification of the Stat1 SH2 domain broadly improves interferon efficacy in proportion to p300/CREB-binding protein coactivator recruitment

21 January 2018

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Tyrosine phosphorylation is required for functional activation of disulfide-containing constitutively active STAT mutants

21 January 2018

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Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3.

21 January 2018

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Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M606940200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956893%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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