Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials. (Q40243706)

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scientific article published on 12 April 2017

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English	Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials.	scientific article published on 12 April 2017

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scholarly article

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17 March 2020

Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials (English)

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17 March 2020

colorectal cancer

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based on heuristic

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based on heuristic

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metastatic colon cancer

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based on heuristic

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colorectal carcinoma

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based on heuristic

inferred from title

1

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17 March 2020

4

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17 March 2020

Jean-Pierre Pignon

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17 March 2020

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B Lueza

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17 March 2020

J-Y Douillard

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17 March 2020

H-J Lenz

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17 March 2020

A Venook

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17 March 2020

V Heinemann

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17 March 2020

E Van Cutsem

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17 March 2020

A Cervantes

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17 March 2020

F Ciardiello

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17 March 2020

J Tabernero

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17 March 2020

publication date

1 August 2017

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17 March 2020

Annals of Oncology

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17 March 2020

28

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17 March 2020

8

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17 March 2020

1713-1729

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17 March 2020

Outcome according to KRAS-, NRAS- and BRAF-mutation as well as KRAS mutation variants: pooled analysis of five randomized trials in metastatic colorectal cancer by the AIO colorectal cancer study group

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of 17,641 patients with right- and left-sided colon cancer: differences in epidemiology, perioperative course, histology, and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic and Predictive Relevance of Primary Tumor Location in Patients With RAS Wild-Type Metastatic Colorectal Cancer: Retrospective Analyses of the CRYSTAL and FIRE-3 Trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are there two sides to colorectal cancer?

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbiota organization is a distinct feature of proximal colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying heterogeneity in a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucinous subtype as prognostic factor in colorectal cancer: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorouracil, leucovorin, and irinotecan plus cetuximab treatment and RAS mutations in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

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Analysis of KRAS/NRAS Mutations in a Phase III Study of Panitumumab with FOLFIRI Compared with FOLFIRI Alone as Second-line Treatment for Metastatic Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

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A critical review of methods for the assessment of patient-level interactions in individual participant data meta-analysis of randomized trials, and guidance for practitioners.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

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A comparison of colon and rectal somatic DNA alterations

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcome of patients with metastatic colorectal cancer depends on the primary tumor site (midgut vs. hindgut): analysis of the FIRE1-trial (FuFIRI or mIROX as first-line treatment)

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relevance of primary tumour location in patients with metastatic colorectal cancer: A meta-analysis of first-line clinical trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of Primary Tumor Site on Bevacizumab Efficacy in Metastatic Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prognostic analysis of 895 cases of stage III colon cancer in different colon subsites

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary tumor location as a prognostic factor in metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible better long-term survival in left versus right-sided colon cancer - a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized controlled trial of cetuximab plus chemotherapy for patients with KRAS wild-type unresectable colorectal liver-limited metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The consensus molecular subtypes of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary tumor site is a useful predictor of cetuximab efficacy in the third-line or salvage treatment of KRAS wild-type (exon 2 non-mutant) metastatic colorectal cancer: a nationwide cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FOLFOX4 plus cetuximab treatment and RAS mutations in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of vertebrate left-right asymmetry

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ESMO consensus guidelines for the management of patients with metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Map of differential transcript expression in the normal human large intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Final results from PRIME: randomized phase III study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colorectal cancer incidence trends in the United States and United kingdom: evidence of right- to left-sided biological gradients with implications for screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant KRAS codon 12 and 13 alleles in patients with metastatic colorectal cancer: assessment as prognostic and predictive biomarkers of response to panitumumab

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex- and gender-specific disparities in colorectal cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary tumor location and bevacizumab effectiveness in patients with metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Left and right sided large bowel cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic Survival Associated With Left-Sided vs Right-Sided Colon Cancer: A Systematic Review and Meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PEAK: a randomized, multicenter phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-type KRAS exon 2 metastatic color

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oncosurgery approach to managing liver metastases from colorectal cancer: a multidisciplinary international consensus

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Location of Primary Tumor and Benefit From Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early tumour shrinkage (ETS) and depth of response (DpR) in the treatment of patients with metastatic colorectal cancer (mCRC).

1 reference

https://pubmed.ncbi.nlm.nih.gov/28407110

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1093/ANNONC/MDX175

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17 March 2020

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17 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28407110%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

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